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A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans.
Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y, Wijmenga C, Netea MG, Kumar V. Jaeger M, et al. J Infect Dis. 2019 Jul 31;220(5):862-872. doi: 10.1093/infdis/jiz206. J Infect Dis. 2019. PMID: 31241743 Free PMC article.
A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis.
Jaeger M, Pinelli M, Borghi M, Constantini C, Dindo M, van Emst L, Puccetti M, Pariano M, Ricaño-Ponce I, Büll C, Gresnigt MS, Wang X, Gutierrez Achury J, Jacobs CWM, Xu N, Oosting M, Arts P, Joosten LAB, van de Veerdonk FL, Veltman JA, Ten Oever J, Kullberg BJ, Feng M, Adema GJ, Wijmenga C, Kumar V, Sobel J, Gilissen C, Romani L, Netea MG. Jaeger M, et al. Sci Transl Med. 2019 Jun 12;11(496):eaar3558. doi: 10.1126/scitranslmed.aar3558. Sci Transl Med. 2019. PMID: 31189718
The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. Jaeger M, et al. Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25579795 Free PMC article.
A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
Li Y, Oosting M, Smeekens SP, Jaeger M, Aguirre-Gamboa R, Le KTT, Deelen P, Ricaño-Ponce I, Schoffelen T, Jansen AFM, Swertz MA, Withoff S, van de Vosse E, van Deuren M, van de Veerdonk F, Zhernakova A, van der Meer JWM, Xavier RJ, Franke L, Joosten LAB, Wijmenga C, Kumar V, Netea MG. Li Y, et al. Among authors: jaeger m. Cell. 2016 Nov 3;167(4):1099-1110.e14. doi: 10.1016/j.cell.2016.10.017. Cell. 2016. PMID: 27814507 Free article.
An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility.
Matzaraki V, Gresnigt MS, Jaeger M, Ricaño-Ponce I, Johnson MD, Oosting M, Franke L, Withoff S, Perfect JR, Joosten LAB, Kullberg BJ, van de Veerdonk FL, Jonkers I, Li Y, Wijmenga C, Netea MG, Kumar V. Matzaraki V, et al. Among authors: jaeger m. PLoS One. 2017 Jul 20;12(7):e0180824. doi: 10.1371/journal.pone.0180824. eCollection 2017. PLoS One. 2017. PMID: 28727728 Free PMC article.
Inflammatory Protein Profiles in Plasma of Candidaemia Patients and the Contribution of Host Genetics to Their Variability.
Matzaraki V, Le KTT, Jaeger M, Aguirre-Gamboa R, Johnson MD, Sanna S, Rosati D, Franke L, Zhernakova A, Fu J, Withoff S, Jonkers I, Li Y, Joosten LAB, Netea MG, Wijmenga C, Kumar V. Matzaraki V, et al. Among authors: jaeger m. Front Immunol. 2021 Aug 26;12:662171. doi: 10.3389/fimmu.2021.662171. eCollection 2021. Front Immunol. 2021. PMID: 34512620 Free PMC article.
Genetic variations in innate immunity genes affect response to Coxiella burnetii and are associated with susceptibility to chronic Q fever.
Jansen AFM, Schoffelen T, Bleeker-Rovers CP, Wever PC, Jaeger M, Oosting M, Adriaans A, Joosten LAB, Netea MG, van Deuren M, van de Vosse E. Jansen AFM, et al. Among authors: jaeger m. Clin Microbiol Infect. 2019 May;25(5):631.e11-631.e15. doi: 10.1016/j.cmi.2018.08.011. Epub 2019 Jan 4. Clin Microbiol Infect. 2019. PMID: 30616015 Free article.
Genetic basis for recurrent vulvo-vaginal candidiasis.
Jaeger M, Plantinga TS, Joosten LA, Kullberg BJ, Netea MG. Jaeger M, et al. Curr Infect Dis Rep. 2013 Apr;15(2):136-42. doi: 10.1007/s11908-013-0319-3. Curr Infect Dis Rep. 2013. PMID: 23354953
808 results