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Co-regulatory networks of human serum proteins link genetics to disease.
Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Aspelund T, Shu L, Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: jennings ll. Science. 2018 Aug 24;361(6404):769-773. doi: 10.1126/science.aaq1327. Epub 2018 Aug 2. Science. 2018. PMID: 30072576 Free PMC article.
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency.
Gonzalez R, Jennings LL, Knuth M, Orth AP, Klock HE, Ou W, Feuerhelm J, Hull MV, Koesema E, Wang Y, Zhang J, Wu C, Cho CY, Su AI, Batalov S, Chen H, Johnson K, Laffitte B, Nguyen DG, Snyder EY, Schultz PG, Harris JL, Lesley SA. Gonzalez R, et al. Among authors: jennings ll. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3552-7. doi: 10.1073/pnas.0914019107. Epub 2010 Feb 2. Proc Natl Acad Sci U S A. 2010. PMID: 20133595 Free PMC article.
Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.
Keulen DV, Pouwer MG, Emilsson V, Matic LP, Pieterman EJ, Hedin U, Gudnason V, Jennings LL, Holmstrøm K, Nielsen BS, Pasterkamp G, Lindeman JHN, van Gool AJ, Sollewijn Gelpke MD, Princen HMG, Tempel D. Keulen DV, et al. Among authors: jennings ll. PLoS One. 2019 Aug 28;14(8):e0221477. doi: 10.1371/journal.pone.0221477. eCollection 2019. PLoS One. 2019. PMID: 31461490 Free PMC article.
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.
Gudmundsdottir V, Zaghlool SB, Emilsson V, Aspelund T, Ilkov M, Gudmundsson EF, Jonsson SM, Zilhão NR, Lamb JR, Suhre K, Jennings LL, Gudnason V. Gudmundsdottir V, et al. Among authors: jennings ll. Diabetes. 2020 Aug;69(8):1843-1853. doi: 10.2337/db19-1070. Epub 2020 May 8. Diabetes. 2020. PMID: 32385057 Free PMC article.
ACE2 levels are altered in comorbidities linked to severe outcome in COVID-19.
Emilsson V, Gudmundsson EF, Aspelund T, Jonsson BG, Gudjonsson A, Launer LJ, Lamb JR, Gudmundsdottir V, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: jennings ll. medRxiv [Preprint]. 2020 Jun 5:2020.06.04.20122044. doi: 10.1101/2020.06.04.20122044. medRxiv. 2020. PMID: 32511628 Free PMC article. Preprint.
It's in Our Blood: A Glimpse of Personalized Medicine.
Lamb JR, Jennings LL, Gudmundsdottir V, Gudnason V, Emilsson V. Lamb JR, et al. Among authors: jennings ll. Trends Mol Med. 2021 Jan;27(1):20-30. doi: 10.1016/j.molmed.2020.09.003. Epub 2020 Sep 25. Trends Mol Med. 2021. PMID: 32988739 Review.
Serum levels of ACE2 are higher in patients with obesity and diabetes.
Emilsson V, Gudmundsson EF, Aspelund T, Jonsson BG, Gudjonsson A, Launer LJ, Lamb JR, Gudmundsdottir V, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: jennings ll. Obes Sci Pract. 2020 Dec 16;7(2):239-243. doi: 10.1002/osp4.472. eCollection 2021 Apr. Obes Sci Pract. 2020. PMID: 33841894 Free PMC article.
63 results