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Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
Pulit SL, Stoneman C, Morris AP, Wood AR, Glastonbury CA, Tyrrell J, Yengo L, Ferreira T, Marouli E, Ji Y, Yang J, Jones S, Beaumont R, Croteau-Chonka DC, Winkler TW; GIANT Consortium; Hattersley AT, Loos RJF, Hirschhorn JN, Visscher PM, Frayling TM, Yaghootkar H, Lindgren CM. Pulit SL, et al. Among authors: ji y. Hum Mol Genet. 2019 Jan 1;28(1):166-174. doi: 10.1093/hmg/ddy327. Hum Mol Genet. 2019. PMID: 30239722 Free PMC article.
A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure.
Frayling TM, Beaumont RN, Jones SE, Yaghootkar H, Tuke MA, Ruth KS, Casanova F, West B, Locke J, Sharp S, Ji Y, Thompson W, Harrison J, Etheridge AS, Gallins PJ, Jima D, Wright F, Zhou Y, Innocenti F, Lindgren CM, Grarup N, Murray A, Freathy RM, Weedon MN, Tyrrell J, Wood AR. Frayling TM, et al. Among authors: ji y. Cell Rep. 2018 Apr 10;23(2):327-336. doi: 10.1016/j.celrep.2018.03.070. Cell Rep. 2018. PMID: 29641994 Free PMC article.
Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension.
Ji Y, Yiorkas AM, Frau F, Mook-Kanamori D, Staiger H, Thomas EL, Atabaki-Pasdar N, Campbell A, Tyrrell J, Jones SE, Beaumont RN, Wood AR, Tuke MA, Ruth KS, Mahajan A, Murray A, Freathy RM, Weedon MN, Hattersley AT, Hayward C, Machann J, Häring HU, Franks P, de Mutsert R, Pearson E, Stefan N, Frayling TM, Allebrandt KV, Bell JD, Blakemore AI, Yaghootkar H. Ji Y, et al. Diabetes. 2019 Jan;68(1):207-219. doi: 10.2337/db18-0708. Epub 2018 Oct 23. Diabetes. 2019. PMID: 30352878 Free article.
Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.
Thompson WD, Beaumont RN, Kuang A, Warrington NM, Ji Y, Tyrrell J, Wood AR, Scholtens DM, Knight BA, Evans DM, Lowe WL Jr, Santorelli G, Azad R, Mason D, Hattersley AT, Frayling TM, Yaghootkar H, Borges MC, Lawlor DA, Freathy RM. Thompson WD, et al. Among authors: ji y. Hum Mol Genet. 2022 Jun 4;31(11):1762-1775. doi: 10.1093/hmg/ddab356. Hum Mol Genet. 2022. PMID: 34897462 Free PMC article.
DNA methylation and inflammation marker profiles associated with a history of depression.
Crawford B, Craig Z, Mansell G, White I, Smith A, Spaull S, Imm J, Hannon E, Wood A, Yaghootkar H, Ji Y; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Mullins N, Lewis CM, Mill J, Murphy TM. Crawford B, et al. Among authors: ji y. Hum Mol Genet. 2018 Aug 15;27(16):2840-2850. doi: 10.1093/hmg/ddy199. Hum Mol Genet. 2018. PMID: 29790996 Free PMC article.
Using genetics to understand the causal influence of higher BMI on depression.
Tyrrell J, Mulugeta A, Wood AR, Zhou A, Beaumont RN, Tuke MA, Jones SE, Ruth KS, Yaghootkar H, Sharp S, Thompson WD, Ji Y, Harrison J, Freathy RM, Murray A, Weedon MN, Lewis C, Frayling TM, Hyppönen E. Tyrrell J, et al. Among authors: ji y. Int J Epidemiol. 2019 Jun 1;48(3):834-848. doi: 10.1093/ije/dyy223. Int J Epidemiol. 2019. PMID: 30423117 Free PMC article.
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.
Jones SE, van Hees VT, Mazzotti DR, Marques-Vidal P, Sabia S, van der Spek A, Dashti HS, Engmann J, Kocevska D, Tyrrell J, Beaumont RN, Hillsdon M, Ruth KS, Tuke MA, Yaghootkar H, Sharp SA, Ji Y, Harrison JW, Freathy RM, Murray A, Luik AI, Amin N, Lane JM, Saxena R, Rutter MK, Tiemeier H, Kutalik Z, Kumari M, Frayling TM, Weedon MN, Gehrman PR, Wood AR. Jones SE, et al. Among authors: ji y. Nat Commun. 2019 Apr 5;10(1):1585. doi: 10.1038/s41467-019-09576-1. Nat Commun. 2019. PMID: 30952852 Free PMC article.
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.
Thompson WD, Beaumont RN, Kuang A, Warrington NM, Ji Y, Tyrrell J, Wood AR, Scholtens DM, Knight BA, Evans DM, Lowe WL Jr, Santorelli G, Azad R, Mason D, Hattersley AT, Frayling TM, Yaghootkar H, Borges MC, Lawlor DA, Freathy RM. Thompson WD, et al. Among authors: ji y. Diabetologia. 2021 Dec;64(12):2790-2802. doi: 10.1007/s00125-021-05570-9. Epub 2021 Sep 20. Diabetologia. 2021. PMID: 34542646 Free PMC article.
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