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Sensitive and accurate liquid chromatography-tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine.
Jiang H, Demers R, Kandoussi H, Burrell R, Eley T, Kadiyala P, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME, Zeng J. Jiang H, et al. J Pharm Biomed Anal. 2015 Mar 25;107:17-23. doi: 10.1016/j.jpba.2014.12.011. Epub 2014 Dec 17. J Pharm Biomed Anal. 2015. PMID: 25562845
Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma.
Jiang H, Kandoussi H, Zeng J, Wang J, Demers R, Eley T, He B, Burrell R, Easter J, Kadiyala P, Pursley J, Cojocaru L, Baker C, Ryan J, Aubry AF, Arnold ME. Jiang H, et al. J Pharm Biomed Anal. 2015 Mar 25;107:409-18. doi: 10.1016/j.jpba.2015.01.027. Epub 2015 Jan 20. J Pharm Biomed Anal. 2015. PMID: 25676854
A highly sensitive and selective LC-MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies.
Kandoussi H, Jiang H, Zeng J, Zheng N, Kadiyala P, Eley T, He B, Garimella T, Demers R, Cojocaru L, Aubry AF, Arnold ME. Kandoussi H, et al. Among authors: jiang h. J Pharm Biomed Anal. 2016 Feb 5;119:145-51. doi: 10.1016/j.jpba.2015.11.028. Epub 2015 Nov 23. J Pharm Biomed Anal. 2016. PMID: 26683987
A rugged and accurate liquid chromatography-tandem mass spectrometry method for the determination of asunaprevir, an NS3 protease inhibitor, in plasma.
Yuan L, Jiang H, Ouyang Z, Xia YQ, Zeng J, Peng Q, Lange RW, Deng Y, Arnold ME, Aubry AF. Yuan L, et al. Among authors: jiang h. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Mar 15;921-922:81-6. doi: 10.1016/j.jchromb.2013.01.029. Epub 2013 Feb 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23435345
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