Jochemsen AG - Search Results

1

Interaction between p53 mutation and a somatic HDMX biomarker better defines metastatic potential in breast cancer.

Grawenda AM, Møller EK, Lam S, Repapi E, Teunisse AF, Alnæs GI, Børresen-Dale AL, Kristensen VN, Goding CR, Jochemsen AG, Edvardsen H, Bond GL. Grawenda AM, et al. Among authors: jochemsen ag. Cancer Res. 2015 Feb 15;75(4):698-708. doi: 10.1158/0008-5472.CAN-14-2637. Epub 2015 Feb 3. Cancer Res. 2015. PMID: 25649770

2

FAK Inhibitor-Based Combinations with MEK or PKC Inhibitors Trigger Synergistic Antitumor Effects in Uveal Melanoma.

Tarin M, Némati F, Decaudin D, Canbezdi C, Marande B, Silva L, Derrien H, Jochemsen AG, Gardrat S, Piperno-Neumann S, Rodrigues M, Mariani P, Cassoux N, Stern MH, Roman-Roman S, Alsafadi S. Tarin M, et al. Among authors: jochemsen ag. Cancers (Basel). 2023 Apr 13;15(8):2280. doi: 10.3390/cancers15082280. Cancers (Basel). 2023. PMID: 37190207 Free PMC article.

3

Apoptin, a protein derived from chicken anemia virus, induces p53-independent apoptosis in human osteosarcoma cells.

Zhuang SM, Shvarts A, van Ormondt H, Jochemsen AG, van der Eb AJ, Noteborn MH. Zhuang SM, et al. Among authors: jochemsen ag. Cancer Res. 1995 Feb 1;55(3):486-9. Cancer Res. 1995. PMID: 7834613

4

Wilms' tumor 1-KTS isoforms induce p53-independent apoptosis that can be partially rescued by expression of the epidermal growth factor receptor or the insulin receptor.

Menke AL, Shvarts A, Riteco N, van Ham RC, van der Eb AJ, Jochemsen AG. Menke AL, et al. Among authors: jochemsen ag. Cancer Res. 1997 Apr 1;57(7):1353-63. Cancer Res. 1997. PMID: 9102224

5

Hdmx stabilizes Mdm2 and p53.

Stad R, Ramos YF, Little N, Grivell S, Attema J, van Der Eb AJ, Jochemsen AG. Stad R, et al. Among authors: jochemsen ag. J Biol Chem. 2000 Sep 8;275(36):28039-44. doi: 10.1074/jbc.M003496200. J Biol Chem. 2000. PMID: 10827196 Free article.

6

Aberrant expression of HDMX proteins in tumor cells correlates with wild-type p53.

Ramos YF, Stad R, Attema J, Peltenburg LT, van der Eb AJ, Jochemsen AG. Ramos YF, et al. Among authors: jochemsen ag. Cancer Res. 2001 Mar 1;61(5):1839-42. Cancer Res. 2001. PMID: 11280734

7

Hdmx and Mdm2 can repress transcription activation by p53 but not by p63.

Little NA, Jochemsen AG. Little NA, et al. Among authors: jochemsen ag. Oncogene. 2001 Jul 27;20(33):4576-80. doi: 10.1038/sj.onc.1204615. Oncogene. 2001. PMID: 11494153

8

Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.

Pereg Y, Shkedy D, de Graaf P, Meulmeester E, Edelson-Averbukh M, Salek M, Biton S, Teunisse AF, Lehmann WD, Jochemsen AG, Shiloh Y. Pereg Y, et al. Among authors: jochemsen ag. Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):5056-61. doi: 10.1073/pnas.0408595102. Epub 2005 Mar 23. Proc Natl Acad Sci U S A. 2005. PMID: 15788536 Free PMC article.

9

Loss of HAUSP-mediated deubiquitination contributes to DNA damage-induced destabilization of Hdmx and Hdm2.

Meulmeester E, Maurice MM, Boutell C, Teunisse AF, Ovaa H, Abraham TE, Dirks RW, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell. 2005 May 27;18(5):565-76. doi: 10.1016/j.molcel.2005.04.024. Mol Cell. 2005. PMID: 15916963 Free article.

10

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.

Okamoto K, Kashima K, Pereg Y, Ishida M, Yamazaki S, Nota A, Teunisse A, Migliorini D, Kitabayashi I, Marine JC, Prives C, Shiloh Y, Jochemsen AG, Taya Y. Okamoto K, et al. Among authors: jochemsen ag. Mol Cell Biol. 2005 Nov;25(21):9608-20. doi: 10.1128/MCB.25.21.9608-9620.2005. Mol Cell Biol. 2005. PMID: 16227609 Free PMC article.

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