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Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.
Marques MA, Landim-Vieira M, Moraes AH, Sun B, Johnston JR, Dieseldorff Jones KM, Cino EA, Parvatiyar MS, Valera IC, Silva JL, Galkin VE, Chase PB, Kekenes-Huskey PM, de Oliveira GAP, Pinto JR. Marques MA, et al. Among authors: johnston jr. Chem Sci. 2021 Apr 29;12(21):7308-7323. doi: 10.1039/d1sc01886h. Chem Sci. 2021. PMID: 34163821 Free PMC article.
Structural and functional impact of troponin C-mediated Ca2+ sensitization on myofilament lattice spacing and cross-bridge mechanics in mouse cardiac muscle.
Gonzalez-Martinez D, Johnston JR, Landim-Vieira M, Ma W, Antipova O, Awan O, Irving TC, Bryant Chase P, Pinto JR. Gonzalez-Martinez D, et al. Among authors: johnston jr. J Mol Cell Cardiol. 2018 Oct;123:26-37. doi: 10.1016/j.yjmcc.2018.08.015. Epub 2018 Aug 21. J Mol Cell Cardiol. 2018. PMID: 30138628 Free PMC article.
Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants.
Landim-Vieira M, Johnston JR, Ji W, Mis EK, Tijerino J, Spencer-Manzon M, Jeffries L, Hall EK, Panisello-Manterola D, Khokha MK, Deniz E, Chase PB, Lakhani SA, Pinto JR. Landim-Vieira M, et al. Among authors: johnston jr. Front Physiol. 2020 Jan 22;10:1612. doi: 10.3389/fphys.2019.01612. eCollection 2019. Front Physiol. 2020. PMID: 32038292 Free PMC article.
Hypertrophic Cardiomyopathy Secondary to RAF1 Cysteine-Rich Domain Variants.
Fullenkamp DE, Jorgensen RM, Leach DF, Sinha A, Salamone IM, Johnston JR, Dellefave-Castillo LM, Choudhury L, McNally EM, Wilsbacher LD. Fullenkamp DE, et al. Among authors: johnston jr. Circ Genom Precis Med. 2023 Dec;16(6):e004262. doi: 10.1161/CIRCGEN.123.004262. Epub 2023 Oct 31. Circ Genom Precis Med. 2023. PMID: 37905408 No abstract available.
680 results