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Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.
Nykänen AI, Sandelin H, Krebs R, Keränen MA, Tuuminen R, Kärpänen T, Wu Y, Pytowski B, Koskinen PK, Ylä-Herttuala S, Alitalo K, Lemström KB. Nykänen AI, et al. Among authors: karpanen t. Circulation. 2010 Mar 30;121(12):1413-22. doi: 10.1161/CIRCULATIONAHA.109.910703. Epub 2010 Mar 15. Circulation. 2010. PMID: 20231530
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy.
Karpanen T, Bry M, Ollila HM, Seppänen-Laakso T, Liimatta E, Leskinen H, Kivelä R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Ylä-Herttuala S, Oresic M, Alitalo K. Karpanen T, et al. Circ Res. 2008 Oct 24;103(9):1018-26. doi: 10.1161/CIRCRESAHA.108.178459. Epub 2008 Aug 28. Circ Res. 2008. PMID: 18757827 Free PMC article.
Role of lymphangiogenic factors in tumor metastasis.
He Y, Karpanen T, Alitalo K. He Y, et al. Among authors: karpanen t. Biochim Biophys Acta. 2004 Mar 4;1654(1):3-12. doi: 10.1016/j.bbcan.2003.07.003. Biochim Biophys Acta. 2004. PMID: 14984763 Review.
66 results