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Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.
Klarin D, Busenkell E, Judy R, Lynch J, Levin M, Haessler J, Aragam K, Chaffin M, Haas M, Lindström S, Assimes TL, Huang J, Min Lee K, Shao Q, Huffman JE, Kabrhel C, Huang Y, Sun YV, Vujkovic M, Saleheen D, Miller DR, Reaven P, DuVall S, Boden WE, Pyarajan S, Reiner AP, Trégouët DA, Henke P, Kooperberg C, Gaziano JM, Concato J, Rader DJ, Cho K, Chang KM, Wilson PWF, Smith NL, O'Donnell CJ, Tsao PS, Kathiresan S, Obi A, Damrauer SM, Natarajan P; INVENT Consortium; Veterans Affairs’ Million Veteran Program. Klarin D, et al. Among authors: kabrhel c. Nat Genet. 2019 Nov;51(11):1574-1579. doi: 10.1038/s41588-019-0519-3. Epub 2019 Nov 1. Nat Genet. 2019. PMID: 31676865 Free PMC article.
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
Germain M, Chasman DI, de Haan H, Tang W, Lindström S, Weng LC, de Andrade M, de Visser MC, Wiggins KL, Suchon P, Saut N, Smadja DM, Le Gal G, van Hylckama Vlieg A, Di Narzo A, Hao K, Nelson CP, Rocanin-Arjo A, Folkersen L, Monajemi R, Rose LM, Brody JA, Slagboom E, Aïssi D, Gagnon F, Deleuze JF, Deloukas P, Tzourio C, Dartigues JF, Berr C, Taylor KD, Civelek M, Eriksson P; Cardiogenics Consortium; Psaty BM, Houwing-Duitermaat J, Goodall AH, Cambien F, Kraft P, Amouyel P, Samani NJ, Basu S, Ridker PM, Rosendaal FR, Kabrhel C, Folsom AR, Heit J, Reitsma PH, Trégouët DA, Smith NL, Morange PE. Germain M, et al. Among authors: kabrhel c. Am J Hum Genet. 2015 Apr 2;96(4):532-42. doi: 10.1016/j.ajhg.2015.01.019. Epub 2015 Mar 12. Am J Hum Genet. 2015. PMID: 25772935 Free PMC article.
Is there still room for additional common susceptibility alleles for venous thromboembolism?
Trégouët DA, Delluc A, Roche A, Derbois C, Olaso R, Germain M, de Andrade M, Tang W, Chasman DI, van Hylckama Vlieg A, Reitsma PH, Kabrhel C, Smith N, Morange PE. Trégouët DA, et al. Among authors: kabrhel c. J Thromb Haemost. 2016 Sep;14(9):1798-802. doi: 10.1111/jth.13392. Epub 2016 Aug 6. J Thromb Haemost. 2016. PMID: 27326655 Free PMC article.
A comprehensive survey of genetic variation in 20,691 subjects from four large cohorts.
Lindström S, Loomis S, Turman C, Huang H, Huang J, Aschard H, Chan AT, Choi H, Cornelis M, Curhan G, De Vivo I, Eliassen AH, Fuchs C, Gaziano M, Hankinson SE, Hu F, Jensen M, Kang JH, Kabrhel C, Liang L, Pasquale LR, Rimm E, Stampfer MJ, Tamimi RM, Tworoger SS, Wiggs JL, Hunter DJ, Kraft P. Lindström S, et al. Among authors: kabrhel c. PLoS One. 2017 Mar 16;12(3):e0173997. doi: 10.1371/journal.pone.0173997. eCollection 2017. PLoS One. 2017. PMID: 28301549 Free PMC article.
Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.
Lindström S, Germain M, Crous-Bou M, Smith EN, Morange PE, van Hylckama Vlieg A, de Haan HG, Chasman D, Ridker P, Brody J, de Andrade M, Heit JA, Tang W, DeVivo I, Grodstein F, Smith NL, Tregouet D, Kabrhel C; INVENT Consortium. Lindström S, et al. Among authors: kabrhel c. Hum Genet. 2017 Jul;136(7):897-902. doi: 10.1007/s00439-017-1811-x. Epub 2017 May 20. Hum Genet. 2017. PMID: 28528403 Free PMC article.
Metabolomic analysis of 92 pulmonary embolism patients from a nested case-control study identifies metabolites associated with adverse clinical outcomes.
Zeleznik OA, Poole EM, Lindstrom S, Kraft P, Van Hylckama Vlieg A, Lasky-Su JA, Harrington LB, Hagan K, Kim J, Parry BA, Giordano N, Kabrhel C. Zeleznik OA, et al. Among authors: kabrhel c. J Thromb Haemost. 2018 Mar;16(3):500-507. doi: 10.1111/jth.13937. Epub 2018 Jan 30. J Thromb Haemost. 2018. PMID: 29285876 Free PMC article.
Correction to: Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.
Lindström S, Germain M, Crous-Bou M, Smith EN, Morange PE, van Hylckama Vlieg A, de Haan HG, Chasman D, Ridker P, Brody J, de Andrade M, Heit JA, Tang W, De Vivo I, Grodstein F, Smith NL, Tregouet D, Kabrhel C; INVENT Consortium. Lindström S, et al. Among authors: kabrhel c. Hum Genet. 2018 May;137(5):429. doi: 10.1007/s00439-018-1891-2. Hum Genet. 2018. PMID: 29779052
178 results