Kaplan MH - Search Results

1

STAT4 is expressed in neutrophils and promotes antimicrobial immunity.

Mehrpouya-Bahrami P, Moriarty AK, De Melo P, Keeter WC, Alakhras NS, Nelson AS, Hoover M, Barrios MS, Nadler JL, Serezani CH, Kaplan MH, Galkina EV. Mehrpouya-Bahrami P, et al. Among authors: kaplan mh. JCI Insight. 2021 Jul 22;6(14):e141326. doi: 10.1172/jci.insight.141326. JCI Insight. 2021. PMID: 34138758 Free PMC article.

2

Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways.

Lawless VA, Zhang S, Ozes ON, Bruns HA, Oldham I, Hoey T, Grusby MJ, Kaplan MH. Lawless VA, et al. Among authors: kaplan mh. J Immunol. 2000 Dec 15;165(12):6803-8. doi: 10.4049/jimmunol.165.12.6803. J Immunol. 2000. PMID: 11120802

3

STAT4 requires the N-terminal domain for efficient phosphorylation.

Chang HC, Zhang S, Oldham I, Naeger L, Hoey T, Kaplan MH. Chang HC, et al. Among authors: kaplan mh. J Biol Chem. 2003 Aug 22;278(34):32471-7. doi: 10.1074/jbc.M302776200. Epub 2003 Jun 12. J Biol Chem. 2003. PMID: 12805384 Free article.

4

Signal transducer and activator of transcription (Stat)-6-dependent, but not Stat4-dependent, immunity is required for the development of autoimmunity in Graves' hyperthyroidism.

Land KJ, Moll JS, Kaplan MH, Seetharamaiah GS. Land KJ, et al. Among authors: kaplan mh. Endocrinology. 2004 Aug;145(8):3724-30. doi: 10.1210/en.2004-0352. Epub 2004 Apr 29. Endocrinology. 2004. PMID: 15117875

5

STAT4: a critical regulator of inflammation in vivo.

Kaplan MH. Kaplan MH. Immunol Res. 2005;31(3):231-42. doi: 10.1385/IR:31:3:231. Immunol Res. 2005. PMID: 15888914 Review.

6

Stat4 limits DNA methyltransferase recruitment and DNA methylation of the IL-18Ralpha gene during Th1 differentiation.

Yu Q, Thieu VT, Kaplan MH. Yu Q, et al. Among authors: kaplan mh. EMBO J. 2007 Apr 18;26(8):2052-60. doi: 10.1038/sj.emboj.7601653. Epub 2007 Mar 22. EMBO J. 2007. PMID: 17380127 Free PMC article.

7

Stat3 and Stat4 direct development of IL-17-secreting Th cells.

Mathur AN, Chang HC, Zisoulis DG, Stritesky GL, Yu Q, O'Malley JT, Kapur R, Levy DE, Kansas GS, Kaplan MH. Mathur AN, et al. Among authors: kaplan mh. J Immunol. 2007 Apr 15;178(8):4901-7. doi: 10.4049/jimmunol.178.8.4901. J Immunol. 2007. PMID: 17404271

8

Impaired development of human Th1 cells in patients with deficient expression of STAT4.

Chang HC, Han L, Goswami R, Nguyen ET, Pelloso D, Robertson MJ, Kaplan MH. Chang HC, et al. Among authors: kaplan mh. Blood. 2009 Jun 4;113(23):5887-90. doi: 10.1182/blood-2008-09-179820. Epub 2009 Apr 9. Blood. 2009. PMID: 19359411 Free PMC article.

9

Temporal induction pattern of STAT4 target genes defines potential for Th1 lineage-specific programming.

Good SR, Thieu VT, Mathur AN, Yu Q, Stritesky GL, Yeh N, O'Malley JT, Perumal NB, Kaplan MH. Good SR, et al. Among authors: kaplan mh. J Immunol. 2009 Sep 15;183(6):3839-47. doi: 10.4049/jimmunol.0901411. Epub 2009 Aug 26. J Immunol. 2009. PMID: 19710469 Free PMC article.

10

Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.

Pham D, Yu Q, Walline CC, Muthukrishnan R, Blum JS, Kaplan MH. Pham D, et al. Among authors: kaplan mh. J Immunol. 2013 Jul 15;191(2):902-11. doi: 10.4049/jimmunol.1203229. Epub 2013 Jun 14. J Immunol. 2013. PMID: 23772023 Free PMC article.

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