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Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use.
Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD, Liu M; CHD Exome+ Consortium; Consortium for Genetics of Smoking Behaviour; Barnes DR, Bertelsen S, Chou YL, Erzurumluoglu AM, Faul JD, Haessler J, Hammerschlag AR, Hsu C, Kapoor M, Lai D, Le N, de Leeuw CA, Loukola A, Mangino M, Melbourne CA, Pistis G, Qaiser B, Rohde R, Shao Y, Stringham H, Wetherill L, Zhao W, Agrawal A, Bierut L, Chen C, Eaton CB, Goate A, Haiman C, Heath A, Iacono WG, Martin NG, Polderman TJ, Reiner A, Rice J, Schlessinger D, Scholte HS, Smith JA, Tardif JC, Tindle HA, van der Leij AR, Boehnke M, Chang-Claude J, Cucca F, David SP, Foroud T, Howson JMM, Kardia SLR, Kooperberg C, Laakso M, Lettre G, Madden P, McGue M, North K, Posthuma D, Spector T, Stram D, Tobin MD, Weir DR, Kaprio J, Abecasis GR, Liu DJ, Vrieze S. Brazel DM, et al. Among authors: kapoor m. Biol Psychiatry. 2019 Jun 1;85(11):946-955. doi: 10.1016/j.biopsych.2018.11.024. Epub 2018 Dec 6. Biol Psychiatry. 2019. PMID: 30679032 Free PMC article.
Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.
Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, Hinrichs A, Agrawal A, Brooks A, Chorlian D, Dick D, Hesselbrock V, Foroud T, Kramer J, Kuperman S, Manz N, Nurnberger J Jr, Porjesz B, Rice J, Tischfield J, Xuei X, Schuckit M, Edenberg HJ, Bierut LJ, Goate AM. Kapoor M, et al. PLoS One. 2012;7(3):e33513. doi: 10.1371/journal.pone.0033513. Epub 2012 Mar 16. PLoS One. 2012. PMID: 22438940 Free PMC article.
The genetics of substance dependence.
Wang JC, Kapoor M, Goate AM. Wang JC, et al. Among authors: kapoor m. Annu Rev Genomics Hum Genet. 2012;13:241-61. doi: 10.1146/annurev-genom-090711-163844. Epub 2012 Jun 11. Annu Rev Genomics Hum Genet. 2012. PMID: 22703173 Free PMC article. Review.
A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53.
Wang JC, Foroud T, Hinrichs AL, Le NX, Bertelsen S, Budde JP, Harari O, Koller DL, Wetherill L, Agrawal A, Almasy L, Brooks AI, Bucholz K, Dick D, Hesselbrock V, Johnson EO, Kang S, Kapoor M, Kramer J, Kuperman S, Madden PA, Manz N, Martin NG, McClintick JN, Montgomery GW, Nurnberger JI Jr, Rangaswamy M, Rice J, Schuckit M, Tischfield JA, Whitfield JB, Xuei X, Porjesz B, Heath AC, Edenberg HJ, Bierut LJ, Goate AM. Wang JC, et al. Among authors: kapoor m. Mol Psychiatry. 2013 Nov;18(11):1218-24. doi: 10.1038/mp.2012.143. Epub 2012 Oct 23. Mol Psychiatry. 2013. PMID: 23089632 Free PMC article.
A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.
Kapoor M, Wang JC, Wetherill L, Le N, Bertelsen S, Hinrichs AL, Budde J, Agrawal A, Bucholz K, Dick D, Harari O, Hesselbrock V, Kramer J, Nurnberger JI Jr, Rice J, Saccone N, Schuckit M, Tischfield J, Porjesz B, Edenberg HJ, Bierut L, Foroud T, Goate A. Kapoor M, et al. Hum Genet. 2013 Oct;132(10):1141-51. doi: 10.1007/s00439-013-1318-z. Epub 2013 Jun 7. Hum Genet. 2013. PMID: 23743675 Free PMC article.
Family-based association analysis of alcohol dependence criteria and severity.
Wetherill L, Kapoor M, Agrawal A, Bucholz K, Koller D, Bertelsen SE, Le N, Wang JC, Almasy L, Hesselbrock V, Kramer J, Nurnberger JI Jr, Schuckit M, Tischfield JA, Xuei X, Porjesz B, Edenberg HJ, Goate AM, Foroud T. Wetherill L, et al. Among authors: kapoor m. Alcohol Clin Exp Res. 2014 Feb;38(2):354-66. doi: 10.1111/acer.12251. Epub 2013 Sep 9. Alcohol Clin Exp Res. 2014. PMID: 24015780 Free PMC article.
Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry.
Wang JC, Spiegel N, Bertelsen S, Le N, McKenna N, Budde JP, Harari O, Kapoor M, Brooks A, Hancock D, Tischfield J, Foroud T, Bierut LJ, Steinbach JH, Edenberg HJ, Traynor BJ, Goate AM. Wang JC, et al. Among authors: kapoor m. PLoS One. 2013 Nov 26;8(11):e80204. doi: 10.1371/journal.pone.0080204. eCollection 2013. PLoS One. 2013. PMID: 24303001 Free PMC article.
DSM-5 cannabis use disorder: a phenotypic and genomic perspective.
Agrawal A, Lynskey MT, Bucholz KK, Kapoor M, Almasy L, Dick DM, Edenberg HJ, Foroud T, Goate A, Hancock DB, Hartz S, Johnson EO, Hesselbrock V, Kramer JR, Kuperman S, Nurnberger JI Jr, Schuckit M, Bierut LJ. Agrawal A, et al. Among authors: kapoor m. Drug Alcohol Depend. 2014 Jan 1;134:362-369. doi: 10.1016/j.drugalcdep.2013.11.008. Epub 2013 Nov 16. Drug Alcohol Depend. 2014. PMID: 24315570 Free PMC article.
Association of substance dependence phenotypes in the COGA sample.
Wetherill L, Agrawal A, Kapoor M, Bertelsen S, Bierut LJ, Brooks A, Dick D, Hesselbrock M, Hesselbrock V, Koller DL, Le N, Nurnberger JI Jr, Salvatore JE, Schuckit M, Tischfield JA, Wang JC, Xuei X, Edenberg HJ, Porjesz B, Bucholz K, Goate AM, Foroud T. Wetherill L, et al. Among authors: kapoor m. Addict Biol. 2015 May;20(3):617-27. doi: 10.1111/adb.12153. Epub 2014 May 16. Addict Biol. 2015. PMID: 24832863 Free PMC article.
780 results