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Effect of Hormonal Contraception on Pharmacokinetics of Vaginal Tenofovir in Healthy Women: Increased Tenofovir Diphosphate in Injectable Depot Medroxyprogesterone Acetate Users.
Thurman AR, Schwartz JL, Brache V, Chen BA, Chandra N, Kashuba ADM, Weiner DH, Mauck C, Doncel GF. Thurman AR, et al. Among authors: kashuba adm. J Acquir Immune Defic Syndr. 2019 Jan 1;80(1):79-88. doi: 10.1097/QAI.0000000000001864. J Acquir Immune Defic Syndr. 2019. PMID: 30212395 Clinical Trial.
Absence of sustained hyperlactatemia in HIV-infected patients with risk factors for mitochondrial toxicity.
Wohl DA, Pilcher CD, Evans S, Revuelta M, McComsey G, Yang Y, Zackin R, Alston B, Welch S, Basar M, Kashuba A, Kondo P, Martinez A, Giardini J, Quinn J, Littles M, Wingfield H, Koletar SL; Adult AIDS Clinical Trials Group A5129 Team. Wohl DA, et al. J Acquir Immune Defic Syndr. 2004 Mar 1;35(3):274-8. doi: 10.1097/00126334-200403010-00008. J Acquir Immune Defic Syndr. 2004. PMID: 15076242 Clinical Trial.
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.
Yeh RF, Gaver VE, Patterson KB, Rezk NL, Baxter-Meheux F, Blake MJ, Eron JJ Jr, Klein CE, Rublein JC, Kashuba AD. Yeh RF, et al. J Acquir Immune Defic Syndr. 2006 May;42(1):52-60. doi: 10.1097/01.qai.0000219774.20174.64. J Acquir Immune Defic Syndr. 2006. PMID: 16639344
The pharmacokinetics and viral activity of tenofovir in the male genital tract.
Vourvahis M, Tappouni HL, Patterson KB, Chen YC, Rezk NL, Fiscus SA, Kearney BP, Rooney JF, Hui J, Cohen MS, Kashuba AD. Vourvahis M, et al. J Acquir Immune Defic Syndr. 2008 Mar 1;47(3):329-33. doi: 10.1097/QAI.0b013e3181632cc3. J Acquir Immune Defic Syndr. 2008. PMID: 18197124 Free PMC article. Clinical Trial.
265 results