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Identification of genetic heterogeneity of Alzheimer's disease across age.
Lo MT, Kauppi K, Fan CC, Sanyal N, Reas ET, Sundar VS, Lee WC, Desikan RS, McEvoy LK, Chen CH; Alzheimer's Disease Genetics Consortium. Lo MT, et al. Among authors: kauppi k. Neurobiol Aging. 2019 Dec;84:243.e1-243.e9. doi: 10.1016/j.neurobiolaging.2019.02.022. Epub 2019 Mar 12. Neurobiol Aging. 2019. PMID: 30979435 Free PMC article.
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.
Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. Lo MT, et al. Among authors: kauppi k. Nat Genet. 2017 Jan;49(1):152-156. doi: 10.1038/ng.3736. Epub 2016 Dec 5. Nat Genet. 2017. PMID: 27918536 Free PMC article.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Desikan RS, et al. Among authors: kauppi k. PLoS Med. 2017 Mar 21;14(3):e1002258. doi: 10.1371/journal.pmed.1002258. eCollection 2017 Mar. PLoS Med. 2017. PMID: 28323831 Free PMC article.
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function.
Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, Chen CH, Ueland T, Jönsson EG, Djurovic S, Deary IJ, Dale AM, Andreassen OA; NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group. Smeland OB, et al. Among authors: kauppi k. JAMA Psychiatry. 2017 Oct 1;74(10):1065-1075. doi: 10.1001/jamapsychiatry.2017.1986. JAMA Psychiatry. 2017. PMID: 28746715 Free PMC article.
Polygenic hazard scores in preclinical Alzheimer disease.
Tan CH, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Tan CH, et al. Among authors: kauppi k. Ann Neurol. 2017 Sep;82(3):484-488. doi: 10.1002/ana.25029. Ann Neurol. 2017. PMID: 28940650 Free PMC article.
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative. Tan CH, et al. Among authors: kauppi k. Acta Neuropathol. 2018 Jan;135(1):85-93. doi: 10.1007/s00401-017-1789-4. Epub 2017 Nov 24. Acta Neuropathol. 2018. PMID: 29177679 Free PMC article.
Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease.
Kauppi K, Fan CC, McEvoy LK, Holland D, Tan CH, Chen CH, Andreassen OA, Desikan RS, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Kauppi K, et al. Front Neurosci. 2018 Apr 30;12:260. doi: 10.3389/fnins.2018.00260. eCollection 2018. Front Neurosci. 2018. PMID: 29760643 Free PMC article.
49 results