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Page 1
Genetic Variants Associated With Immunosuppressant Pharmacokinetics and Adverse Effects in the DeKAF Genomics Genome-wide Association Studies.
Oetting WS, Wu B, Schladt DP, Guan W, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Jacobson PA; DeKAF Genomics and GEN-03 Investigators. Oetting WS, et al. Among authors: keating bj. Transplantation. 2019 Jun;103(6):1131-1139. doi: 10.1097/TP.0000000000002625. Transplantation. 2019. PMID: 30801552 Free PMC article.
Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles.
Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA; DeKAF Investigators. Oetting WS, et al. Among authors: keating bj. Am J Transplant. 2016 Feb;16(2):574-82. doi: 10.1111/ajt.13495. Epub 2015 Oct 20. Am J Transplant. 2016. PMID: 26485092 Free PMC article.
Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies.
Li YR, van Setten J, Verma SS, Lu Y, Holmes MV, Gao H, Lek M, Nair N, Chandrupatla H, Chang B, Karczewski KJ, Wong C, Mohebnasab M, Mukhtar E, Phillips R, Tragante V, Hou C, Steel L, Lee T, Garifallou J, Guettouche T, Cao H, Guan W, Himes A, van Houten J, Pasquier A, Yu R, Carrigan E, Miller MB, Schladt D, Akdere A, Gonzalez A, Llyod KM, McGinn D, Gangasani A, Michaud Z, Colasacco A, Snyder J, Thomas K, Wang T, Wu B, Alzahrani AJ, Al-Ali AK, Al-Muhanna FA, Al-Rubaish AM, Al-Mueilo S, Monos DS, Murphy B, Olthoff KM, Wijmenga C, Webster T, Kamoun M, Balasubramanian S, Lanktree MB, Oetting WS, Garcia-Pavia P, MacArthur DG, de Bakker PI, Hakonarson H, Birdwell KA, Jacobson PA, Ritchie MD, Asselbergs FW, Israni AK, Shaked A, Keating BJ. Li YR, et al. Among authors: keating bj. Genome Med. 2015 Oct 1;7:90. doi: 10.1186/s13073-015-0211-x. Genome Med. 2015. PMID: 26423053 Free PMC article.
Pharmacogenomics in kidney transplant recipients and potential for integration into practice.
Nguyen TT, Pearson RA, Mohamed ME, Schladt DP, Berglund D, Rivers Z, Skaar DJ, Wu B, Guan W, van Setten J, Keating BJ, Dorr C, Remmel RP, Matas AJ, Mannon RB, Israni AK, Oetting WS, Jacobson PA. Nguyen TT, et al. Among authors: keating bj. J Clin Pharm Ther. 2020 Dec;45(6):1457-1465. doi: 10.1111/jcpt.13223. Epub 2020 Jul 14. J Clin Pharm Ther. 2020. PMID: 32662547 Free PMC article.
The impact of donor and recipient common clinical and genetic variation on estimated glomerular filtration rate in a European renal transplant population.
Stapleton CP, Heinzel A, Guan W, van der Most PJ, van Setten J, Lord GM, Keating BJ, Israni AK, de Borst MH, Bakker SJL, Snieder H, Weale ME, Delaney F, Hernandez-Fuentes MP, Reindl-Schwaighofer R, Oberbauer R, Jacobson PA, Mark PB, Chapman FA, Phelan PJ, Kennedy C, Sexton D, Murray S, Jardine A, Traynor JP, McKnight AJ, Maxwell AP, Smyth LJ, Oetting WS, Matas AJ, Mannon RB, Schladt DP, Iklé DN, Cavalleri GL, Conlon PJ; UK Ireland Renal Transplant Consortium; DeKAF Genomics and GEN03 Studies; International Genetics and Translational Research in Transplantation Network. Stapleton CP, et al. Among authors: keating bj. Am J Transplant. 2019 Aug;19(8):2262-2273. doi: 10.1111/ajt.15326. Epub 2019 Mar 28. Am J Transplant. 2019. PMID: 30920136 Free PMC article.
Tacrolimus troughs and genetic determinants of metabolism in kidney transplant recipients: A comparison of four ancestry groups.
Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating BJ, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA; DeKAF Genomics and GEN03 Investigators. Mohamed ME, et al. Among authors: keating bj. Am J Transplant. 2019 Oct;19(10):2795-2804. doi: 10.1111/ajt.15385. Epub 2019 May 13. Am J Transplant. 2019. PMID: 30953600 Free PMC article.
NPHP1 (Nephrocystin-1) Gene Deletions Cause Adult-Onset ESRD.
Snoek R, van Setten J, Keating BJ, Israni AK, Jacobson PA, Oetting WS, Matas AJ, Mannon RB, Zhang Z, Zhang W, Hao K, Murphy B, Reindl-Schwaighofer R, Heinzl A, Oberbauer R, Viklicky O, Conlon PJ, Stapleton CP, Bakker SJL, Snieder H, Peters EDJ, van der Zwaag B, Knoers NVAM, de Borst MH, van Eerde AM. Snoek R, et al. Among authors: keating bj. J Am Soc Nephrol. 2018 Jun;29(6):1772-1779. doi: 10.1681/ASN.2017111200. Epub 2018 Apr 13. J Am Soc Nephrol. 2018. PMID: 29654215 Free PMC article.
Donor and recipient polygenic risk scores influence the risk of post-transplant diabetes.
Shaked A, Loza BL, Van Loon E, Olthoff KM, Guan W, Jacobson PA, Zhu A, Fishman CE, Gao H, Oetting WS, Israni AK, Testa G, Trotter J, Klintmalm G, Naesens M, Asrani SK, Keating BJ. Shaked A, et al. Among authors: keating bj. Nat Med. 2022 May;28(5):999-1005. doi: 10.1038/s41591-022-01758-7. Epub 2022 Apr 7. Nat Med. 2022. PMID: 35393535
Genome-wide non-HLA donor-recipient genetic differences influence renal allograft survival via early allograft fibrosis.
Zhang Z, Menon MC, Zhang W, Stahl E, Loza BL, Rosales IA, Yi Z, Banu K, Garzon F, Sun Z, Wei C, Huang W, Lin Q, Israni A, Keating BJ, Colvin RB, Hao K, Murphy B. Zhang Z, et al. Among authors: keating bj. Kidney Int. 2020 Sep;98(3):758-768. doi: 10.1016/j.kint.2020.04.039. Epub 2020 May 23. Kidney Int. 2020. PMID: 32454123 Free PMC article.
121 results