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Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.
Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH; IBSEN Study Group; Stokkers PC, Vermeire S, Mathew CG, Lie BA, Beuers U, Manns MP, Schreiber S, Schrumpf E, Häussinger D, Franke A, Karlsen TH. Hov JR, et al. Among authors: keitel v. PLoS One. 2010 Aug 25;5(8):e12403. doi: 10.1371/journal.pone.0012403. PLoS One. 2010. PMID: 20811628 Free PMC article.
TGR5 sequence variation in primary sclerosing cholangitis.
Hov JR, Keitel V, Schrumpf E, Häussinger D, Karlsen TH. Hov JR, et al. Among authors: keitel v. Dig Dis. 2011;29(1):78-84. doi: 10.1159/000324138. Epub 2011 Jun 17. Dig Dis. 2011. PMID: 21691110 Review.
Characterization of animal models for primary sclerosing cholangitis (PSC).
Fickert P, Pollheimer MJ, Beuers U, Lackner C, Hirschfield G, Housset C, Keitel V, Schramm C, Marschall HU, Karlsen TH, Melum E, Kaser A, Eksteen B, Strazzabosco M, Manns M, Trauner M; International PSC Study Group (IPSCSG). Fickert P, et al. Among authors: keitel v. J Hepatol. 2014 Jun;60(6):1290-303. doi: 10.1016/j.jhep.2014.02.006. Epub 2014 Feb 19. J Hepatol. 2014. PMID: 24560657 Free PMC article. Review.
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.
Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP, Vogel M, Schoonjans K, Lautwein T, Köhrer K, Häussinger D, Luedde T, Heikenwalder M, Keitel V. Reich M, et al. Among authors: keitel v. J Hepatol. 2021 Sep;75(3):634-646. doi: 10.1016/j.jhep.2021.03.029. Epub 2021 Apr 17. J Hepatol. 2021. PMID: 33872692 Free article.
TGR5 in the biliary tree.
Keitel V, Häussinger D. Keitel V, et al. Dig Dis. 2011;29(1):45-7. doi: 10.1159/000324127. Epub 2011 Jun 17. Dig Dis. 2011. PMID: 21691103 Review.
Perspective: TGR5 (Gpbar-1) in liver physiology and disease.
Keitel V, Häussinger D. Keitel V, et al. Clin Res Hepatol Gastroenterol. 2012 Oct;36(5):412-9. doi: 10.1016/j.clinre.2012.03.008. Epub 2012 Apr 18. Clin Res Hepatol Gastroenterol. 2012. PMID: 22521118 Review.
TGR5 in cholangiocytes.
Keitel V, Häussinger D. Keitel V, et al. Curr Opin Gastroenterol. 2013 May;29(3):299-304. doi: 10.1097/MOG.0b013e32835f3f14. Curr Opin Gastroenterol. 2013. PMID: 23429467 Review.
184 results