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Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
Perera ND, Sheean RK, Scott JW, Kemp BE, Horne MK, Turner BJ. Perera ND, et al. Among authors: kemp be. PLoS One. 2014 Mar 4;9(3):e90449. doi: 10.1371/journal.pone.0090449. eCollection 2014. PLoS One. 2014. PMID: 24595038 Free PMC article.
AMPK functions as an adenylate charge-regulated protein kinase.
Oakhill JS, Scott JW, Kemp BE. Oakhill JS, et al. Among authors: kemp be. Trends Endocrinol Metab. 2012 Mar;23(3):125-32. doi: 10.1016/j.tem.2011.12.006. Epub 2012 Jan 26. Trends Endocrinol Metab. 2012. PMID: 22284532 Review.
ATP sensitive bi-quinoline activator of the AMP-activated protein kinase.
Scott JW, Oakhill JS, Ling NX, Langendorf CG, Foitzik RC, Kemp BE, Issinger OG. Scott JW, et al. Among authors: kemp be. Biochem Biophys Res Commun. 2014 Jan 10;443(2):435-40. doi: 10.1016/j.bbrc.2013.11.130. Epub 2013 Dec 8. Biochem Biophys Res Commun. 2014. PMID: 24332941
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models.
Perera ND, Sheean RK, Scott JW, Kemp BE, Horne MK, Turner BJ. Perera ND, et al. Among authors: kemp be. PLoS One. 2014 Apr 16;9(4):e95549. doi: 10.1371/journal.pone.0095549. eCollection 2014. PLoS One. 2014. PMID: 24740287 Free PMC article.
Fake Inhibitors: AMPK Activation Trumps Inhibition.
Langendorf CG, Scott JW, Kemp BE. Langendorf CG, et al. Among authors: kemp be. Cell Chem Biol. 2017 Jul 20;24(7):775-777. doi: 10.1016/j.chembiol.2017.07.005. Cell Chem Biol. 2017. PMID: 28732195 Free article.
Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism.
Hoffman NJ, Whitfield J, Janzen NR, Belhaj MR, Galic S, Murray-Segal L, Smiles WJ, Ling NXY, Dite TA, Scott JW, Oakhill JS, Brink R, Kemp BE, Hawley JA. Hoffman NJ, et al. Among authors: kemp be. Mol Metab. 2020 Nov;41:101048. doi: 10.1016/j.molmet.2020.101048. Epub 2020 Jun 29. Mol Metab. 2020. PMID: 32610071 Free PMC article.
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.
Ovens AJ, Gee YS, Ling NXY, Yu D, Hardee JP, Chung JD, Ngoei KRW, Waters NJ, Hoffman NJ, Scott JW, Loh K, Spengler K, Heller R, Parker MW, Lynch GS, Huang F, Galic S, Kemp BE, Baell JB, Oakhill JS, Langendorf CG. Ovens AJ, et al. Among authors: kemp be. Biochem J. 2022 Jun 17;479(11):1181-1204. doi: 10.1042/BCJ20220067. Biochem J. 2022. PMID: 35552369 Free PMC article.
Structure and function of AMP-activated protein kinase.
Oakhill JS, Scott JW, Kemp BE. Oakhill JS, et al. Among authors: kemp be. Acta Physiol (Oxf). 2009 May;196(1):3-14. doi: 10.1111/j.1748-1716.2009.01977.x. Epub 2009 Feb 20. Acta Physiol (Oxf). 2009. PMID: 19245650 Review.
AMPK is a direct adenylate charge-regulated protein kinase.
Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, Kemp BE. Oakhill JS, et al. Among authors: kemp be. Science. 2011 Jun 17;332(6036):1433-5. doi: 10.1126/science.1200094. Science. 2011. PMID: 21680840
419 results