Kenyon V - Search Results

1

Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase.

Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB 2nd, Perry S, Joshi N, Bougie JM, Leister W, Taylor-Fishwick DA, Nadler JL, Holinstat M, Simeonov A, Maloney DJ, Holman TR. Kenyon V, et al. J Med Chem. 2011 Aug 11;54(15):5485-97. doi: 10.1021/jm2005089. Epub 2011 Jul 8. J Med Chem. 2011. PMID: 21739938 Free PMC article.

2

Novel human lipoxygenase inhibitors discovered using virtual screening with homology models.

Kenyon V, Chorny I, Carvajal WJ, Holman TR, Jacobson MP. Kenyon V, et al. J Med Chem. 2006 Feb 23;49(4):1356-63. doi: 10.1021/jm050639j. J Med Chem. 2006. PMID: 16480270

3

Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2.

Vasquez-Martinez Y, Ohri RV, Kenyon V, Holman TR, Sepúlveda-Boza S. Vasquez-Martinez Y, et al. Among authors: kenyon v. Bioorg Med Chem. 2007 Dec 1;15(23):7408-25. doi: 10.1016/j.bmc.2007.07.036. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17869117 Free PMC article.

4

Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.

Rai G, Kenyon V, Jadhav A, Schultz L, Armstrong M, Jameson JB, Hoobler E, Leister W, Simeonov A, Holman TR, Maloney DJ. Rai G, et al. Among authors: kenyon v. J Med Chem. 2010 Oct 28;53(20):7392-404. doi: 10.1021/jm1008852. J Med Chem. 2010. PMID: 20866075 Free PMC article.

5

Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies.

Rai G, Joshi N, Jung JE, Liu Y, Schultz L, Yasgar A, Perry S, Diaz G, Zhang Q, Kenyon V, Jadhav A, Simeonov A, Lo EH, van Leyen K, Maloney DJ, Holman TR. Rai G, et al. Among authors: kenyon v. J Med Chem. 2014 May 22;57(10):4035-48. doi: 10.1021/jm401915r. Epub 2014 May 13. J Med Chem. 2014. PMID: 24684213 Free PMC article.

6

Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes.

Armstrong MM, Diaz G, Kenyon V, Holman TR. Armstrong MM, et al. Among authors: kenyon v. Bioorg Med Chem. 2014 Aug 1;22(15):4293-7. doi: 10.1016/j.bmc.2014.05.025. Epub 2014 May 21. Bioorg Med Chem. 2014. PMID: 24924423 Free PMC article.

7

Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.

Deschamps JD, Kenyon VA, Holman TR. Deschamps JD, et al. Bioorg Med Chem. 2006 Jun 15;14(12):4295-301. doi: 10.1016/j.bmc.2006.01.057. Epub 2006 Feb 24. Bioorg Med Chem. 2006. PMID: 16500106

8

Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation.

Yeung J, Apopa PL, Vesci J, Kenyon V, Rai G, Jadhav A, Simeonov A, Holman TR, Maloney DJ, Boutaud O, Holinstat M. Yeung J, et al. Among authors: kenyon v. Mol Pharmacol. 2012 Mar;81(3):420-30. doi: 10.1124/mol.111.075630. Epub 2011 Dec 9. Mol Pharmacol. 2012. PMID: 22155783 Free PMC article.

9

Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction.

Weaver JR, Holman TR, Imai Y, Jadhav A, Kenyon V, Maloney DJ, Nadler JL, Rai G, Simeonov A, Taylor-Fishwick DA. Weaver JR, et al. Among authors: kenyon v. Mol Cell Endocrinol. 2012 Jul 6;358(1):88-95. doi: 10.1016/j.mce.2012.03.004. Epub 2012 Mar 20. Mol Cell Endocrinol. 2012. PMID: 22502743

10

A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors.

Jameson JB 2nd, Kenyon V, Holman TR. Jameson JB 2nd, et al. Among authors: kenyon v. Anal Biochem. 2015 May 1;476:45-50. doi: 10.1016/j.ab.2015.02.011. Epub 2015 Feb 21. Anal Biochem. 2015. PMID: 25712042 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

60 results

Search Page