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Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.
Nykänen AI, Sandelin H, Krebs R, Keränen MA, Tuuminen R, Kärpänen T, Wu Y, Pytowski B, Koskinen PK, Ylä-Herttuala S, Alitalo K, Lemström KB. Nykänen AI, et al. Among authors: keranen ma. Circulation. 2010 Mar 30;121(12):1413-22. doi: 10.1161/CIRCULATIONAHA.109.910703. Epub 2010 Mar 15. Circulation. 2010. PMID: 20231530
Angiogenic growth factors in cardiac allograft rejection.
Nykänen AI, Tikkanen JM, Krebs R, Keränen MA, Sihvola RK, Sandelin H, Tuuminen R, Raisky O, Koskinen PK, Lemström KB. Nykänen AI, et al. Among authors: keranen ma. Transplantation. 2006 Jul 15;82(1 Suppl):S22-4. doi: 10.1097/01.tp.0000231443.12570.57. Transplantation. 2006. PMID: 16829789 Review.
VEGFR-1 and -2 regulate inflammation, myocardial angiogenesis, and arteriosclerosis in chronically rejecting cardiac allografts.
Raisky O, Nykänen AI, Krebs R, Hollmén M, Keränen MA, Tikkanen JM, Sihvola R, Alhonen L, Salven P, Wu Y, Hicklin DJ, Alitalo K, Koskinen PK, Lemström KB. Raisky O, et al. Among authors: keranen ma. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):819-25. doi: 10.1161/01.ATV.0000260001.55955.6c. Epub 2007 Feb 8. Arterioscler Thromb Vasc Biol. 2007. PMID: 17290032
37 results