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Human Schwann cells exhibit long-term cell survival, are not tumorigenic and promote repair when transplanted into the contused spinal cord.
Bastidas J, Athauda G, De La Cruz G, Chan WM, Golshani R, Berrocal Y, Henao M, Lalwani A, Mannoji C, Assi M, Otero PA, Khan A, Marcillo AE, Norenberg M, Levi AD, Wood PM, Guest JD, Dietrich WD, Bartlett Bunge M, Pearse DD. Bastidas J, et al. Among authors: khan a. Glia. 2017 Aug;65(8):1278-1301. doi: 10.1002/glia.23161. Epub 2017 May 22. Glia. 2017. PMID: 28543541
Phase 1 Safety Trial of Autologous Human Schwann Cell Transplantation in Chronic Spinal Cord Injury.
Gant KL, Guest JD, Palermo AE, Vedantam A, Jimsheleishvili G, Bunge MB, Brooks AE, Anderson KD, Thomas CK, Santamaria AJ, Perez MA, Curiel R, Nash MS, Saraf-Lavi E, Pearse DD, Widerström-Noga E, Khan A, Dietrich WD, Levi AD. Gant KL, et al. Among authors: khan a. J Neurotrauma. 2022 Feb;39(3-4):285-299. doi: 10.1089/neu.2020.7590. Epub 2021 May 3. J Neurotrauma. 2022. PMID: 33757304 Free PMC article. Clinical Trial.
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