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Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.
Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB. Kielczewski JL, et al. Circ Res. 2009 Oct 23;105(9):897-905. doi: 10.1161/CIRCRESAHA.109.199059. Epub 2009 Sep 17. Circ Res. 2009. PMID: 19762684 Free PMC article.
EPCs and pathological angiogenesis: when good cells go bad.
Li Calzi S, Neu MB, Shaw LC, Kielczewski JL, Moldovan NI, Grant MB. Li Calzi S, et al. Microvasc Res. 2010 May;79(3):207-16. doi: 10.1016/j.mvr.2010.02.011. Epub 2010 Feb 25. Microvasc Res. 2010. PMID: 20188747 Free PMC article. Review.
Diabetic retinopathy is associated with bone marrow neuropathy and a depressed peripheral clock.
Busik JV, Tikhonenko M, Bhatwadekar A, Opreanu M, Yakubova N, Caballero S, Player D, Nakagawa T, Afzal A, Kielczewski J, Sochacki A, Hasty S, Li Calzi S, Kim S, Duclas SK, Segal MS, Guberski DL, Esselman WJ, Boulton ME, Grant MB. Busik JV, et al. Among authors: kielczewski j. J Exp Med. 2009 Dec 21;206(13):2897-906. doi: 10.1084/jem.20090889. Epub 2009 Nov 23. J Exp Med. 2009. PMID: 19934019 Free PMC article.
An ocular view of the IGF-IGFBP system.
Nguyen DV, Li Calzi S, Shaw LC, Kielczewski JL, Korah HE, Grant MB. Nguyen DV, et al. Among authors: kielczewski jl. Growth Horm IGF Res. 2013 Jun;23(3):45-52. doi: 10.1016/j.ghir.2013.03.001. Epub 2013 Apr 8. Growth Horm IGF Res. 2013. PMID: 23578754 Free PMC article. Review.
Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization.
Caballero S, Swaney J, Moreno K, Afzal A, Kielczewski J, Stoller G, Cavalli A, Garland W, Hansen G, Sabbadini R, Grant MB. Caballero S, et al. Among authors: kielczewski j. Exp Eye Res. 2009 Mar;88(3):367-77. doi: 10.1016/j.exer.2008.07.012. Epub 2008 Aug 6. Exp Eye Res. 2009. PMID: 18723015 Free PMC article.
Regulation of adult hematopoietic stem cells fate for enhanced tissue-specific repair.
Sengupta N, Caballero S, Sullivan SM, Chang LJ, Afzal A, Li Calzi S, Kielczewski JL, Prabarakan S, Ellis EA, Moldovan L, Moldovan NI, Boulton ME, Grant MB, Scott EW, Harris JR. Sengupta N, et al. Mol Ther. 2009 Sep;17(9):1594-604. doi: 10.1038/mt.2009.145. Epub 2009 Jul 7. Mol Ther. 2009. PMID: 19584817 Free PMC article.
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).
Kielczewski JL, Li Calzi S, Shaw LC, Cai J, Qi X, Ruan Q, Wu L, Liu L, Hu P, Chan-Ling T, Mames RN, Firth S, Baxter RC, Turowski P, Busik JV, Boulton ME, Grant MB. Kielczewski JL, et al. Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8278-86. doi: 10.1167/iovs.11-8167. Invest Ophthalmol Vis Sci. 2011. PMID: 21931131 Free PMC article.
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