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Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP.
Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL. Yu FX, et al. Among authors: kim yc. Cancer Cell. 2014 Jun 16;25(6):822-30. doi: 10.1016/j.ccr.2014.04.017. Epub 2014 May 29. Cancer Cell. 2014. PMID: 24882516 Free PMC article.
Alternative Wnt Signaling Activates YAP/TAZ.
Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Park HW, et al. Among authors: kim yc. Cell. 2015 Aug 13;162(4):780-94. doi: 10.1016/j.cell.2015.07.013. Cell. 2015. PMID: 26276632 Free PMC article.
Metabolism. Differential regulation of mTORC1 by leucine and glutamine.
Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL. Jewell JL, et al. Among authors: kim yc. Science. 2015 Jan 9;347(6218):194-8. doi: 10.1126/science.1259472. Epub 2015 Jan 7. Science. 2015. PMID: 25567907 Free PMC article.
Sestrins inhibit mTORC1 kinase activation through the GATOR complex.
Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV. Parmigiani A, et al. Among authors: kim yc. Cell Rep. 2014 Nov 20;9(4):1281-91. doi: 10.1016/j.celrep.2014.10.019. Cell Rep. 2014. PMID: 25457612 Free PMC article.
3,210 results