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Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression.
Craig JE, Han X, Qassim A, Hassall M, Cooke Bailey JN, Kinzy TG, Khawaja AP, An J, Marshall H, Gharahkhani P, Igo RP Jr, Graham SL, Healey PR, Ong JS, Zhou T, Siggs O, Law MH, Souzeau E, Ridge B, Hysi PG, Burdon KP, Mills RA, Landers J, Ruddle JB, Agar A, Galanopoulos A, White AJR, Willoughby CE, Andrew NH, Best S, Vincent AL, Goldberg I, Radford-Smith G, Martin NG, Montgomery GW, Vitart V, Hoehn R, Wojciechowski R, Jonas JB, Aung T, Pasquale LR, Cree AJ, Sivaprasad S, Vallabh NA; NEIGHBORHOOD consortium; UK Biobank Eye and Vision Consortium; Viswanathan AC, Pasutto F, Haines JL, Klaver CCW, van Duijn CM, Casson RJ, Foster PJ, Khaw PT, Hammond CJ, Mackey DA, Mitchell P, Lotery AJ, Wiggs JL, Hewitt AW, MacGregor S. Craig JE, et al. Among authors: kinzy tg. Nat Genet. 2020 Feb;52(2):160-166. doi: 10.1038/s41588-019-0556-y. Epub 2020 Jan 20. Nat Genet. 2020. PMID: 31959993 Free PMC article.
Pathway Analysis Integrating Genome-Wide and Functional Data Identifies PLCG2 as a Candidate Gene for Age-Related Macular Degeneration.
Waksmunski AR, Grunin M, Kinzy TG, Igo RP Jr, Haines JL, Cooke Bailey JN; International Age-Related Macular Degeneration Genomics Consortium. Waksmunski AR, et al. Among authors: kinzy tg. Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):4041-4051. doi: 10.1167/iovs.19-27827. Invest Ophthalmol Vis Sci. 2019. PMID: 31560769 Free PMC article.
Genetic Risk Scores.
Igo RP Jr, Kinzy TG, Cooke Bailey JN. Igo RP Jr, et al. Among authors: kinzy tg. Curr Protoc Hum Genet. 2019 Dec;104(1):e95. doi: 10.1002/cphg.95. Curr Protoc Hum Genet. 2019. PMID: 31765077 Free PMC article. Review.
The GGLEAM Study: Understanding Glaucoma in the Ohio Amish.
Waksmunski AR, Song YE, Kinzy TG, Laux RA, Sewell J, Fuzzell D, Fuzzell S, Miller S, Wiggs JL, Pasquale LR, Skarie JM, Haines JL, Cooke Bailey JN. Waksmunski AR, et al. Among authors: kinzy tg. Int J Environ Res Public Health. 2021 Feb 6;18(4):1551. doi: 10.3390/ijerph18041551. Int J Environ Res Public Health. 2021. PMID: 33561996 Free PMC article.
Polygenic Risk Scores.
Osterman MD, Kinzy TG, Bailey JNC. Osterman MD, et al. Among authors: kinzy tg. Curr Protoc. 2021 May;1(5):e126. doi: 10.1002/cpz1.126. Curr Protoc. 2021. PMID: 33987971
Development and Evaluation of a Rules-based Algorithm for Primary Open-Angle Glaucoma in the VA Million Veteran Program.
Nealon CL, Halladay CW, Kinzy TG, Simpson P, Canania RL, Anthony SA, Roncone DP, Sawicki Rogers LR, Leber JN, Dougherty JM, Sullivan JM, Wu WC, Greenberg PB, Iyengar SK, Crawford DC, Peachey NS, Cooke Bailey JN; VA Million Veteran Program. Nealon CL, et al. Among authors: kinzy tg. Ophthalmic Epidemiol. 2022 Dec;29(6):640-648. doi: 10.1080/09286586.2021.1992784. Epub 2021 Nov 25. Ophthalmic Epidemiol. 2022. PMID: 34822319 Free PMC article.
117 results