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Vandetanib, designed to inhibit VEGFR2 and EGFR signaling, had no clinical activity as monotherapy for recurrent ovarian cancer and no detectable modulation of VEGFR2.
Annunziata CM, Walker AJ, Minasian L, Yu M, Kotz H, Wood BJ, Calvo K, Choyke P, Kimm D, Steinberg SM, Kohn EC. Annunziata CM, et al. Among authors: kohn ec. Clin Cancer Res. 2010 Jan 15;16(2):664-72. doi: 10.1158/1078-0432.CCR-09-2308. Epub 2010 Jan 12. Clin Cancer Res. 2010. PMID: 20068097 Free PMC article. Clinical Trial.
Ovarian cancer in the proteomics era.
Annunziata CM, Azad N, Dhamoon AS, Whiteley G, Kohn EC. Annunziata CM, et al. Among authors: kohn ec. Int J Gynecol Cancer. 2008 Mar-Apr;18 Suppl 1:1-6. doi: 10.1111/j.1525-1438.2007.01096.x. Int J Gynecol Cancer. 2008. PMID: 18336391 Review.
284 results