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Metabolism of okadaic acid by NADPH-dependent enzymes present in human or rat liver S9 fractions results in different toxic effects.
Toxicol In Vitro. 2017 Aug;42:161-170. doi: 10.1016/j.tiv.2017.04.009. Epub 2017 Apr 14.
Toxicol In Vitro. 2017.
PMID: 28414161
Differences in metabolism of the marine biotoxin okadaic acid by human and rat cytochrome P450 monooxygenases.
Kolrep F, Hessel S, These A, Ehlers A, Rein K, Lampen A.
Kolrep F, et al.
Arch Toxicol. 2016 Aug;90(8):2025-36. doi: 10.1007/s00204-015-1591-9. Epub 2015 Sep 15.
Arch Toxicol. 2016.
PMID: 26374342
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In vitro metabolism of the cyanotoxin cylindrospermopsin in HepaRG cells and liver tissue fractions.
Kittler K, Hurtaud-Pessel D, Maul R, Kolrep F, Fessard V.
Kittler K, et al. Among authors: kolrep f.
Toxicon. 2016 Feb;110:47-50. doi: 10.1016/j.toxicon.2015.11.007. Epub 2015 Dec 2.
Toxicon. 2016.
PMID: 26610396
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In vitro biotransformation of pyrrolizidine alkaloids in different species. Part I: Microsomal degradation.
Kolrep F, Numata J, Kneuer C, Preiss-Weigert A, Lahrssen-Wiederholt M, Schrenk D, These A.
Kolrep F, et al.
Arch Toxicol. 2018 Mar;92(3):1089-1097. doi: 10.1007/s00204-017-2114-7. Epub 2017 Nov 16.
Arch Toxicol. 2018.
PMID: 29143854
Free PMC article.
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Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose-response data.
Menz J, Götz ME, Gündel U, Gürtler R, Herrmann K, Hessel-Pras S, Kneuer C, Kolrep F, Nitzsche D, Pabel U, Sachse B, Schmeisser S, Schumacher DM, Schwerdtle T, Tralau T, Zellmer S, Schäfer B.
Menz J, et al. Among authors: kolrep f.
Arch Toxicol. 2023 Sep;97(9):2303-2328. doi: 10.1007/s00204-023-03553-w. Epub 2023 Jul 5.
Arch Toxicol. 2023.
PMID: 37402810
Free PMC article.
Review.
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Predicting the transfer of contaminants in ruminants by models - potentials and challenges.
Klevenhusen F, Südekum KH, Breves G, Kolrep F, Kietzmann M, Gerletti P, Numata J, Spolders M, Pieper R, Kowalczyk J.
Klevenhusen F, et al. Among authors: kolrep f.
ALTEX. 2021;38(3):398-418. doi: 10.14573/altex.2007081. Epub 2020 Dec 17.
ALTEX. 2021.
PMID: 33330944
Free article.
Review.
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