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A method and server for predicting damaging missense mutations.
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Adzhubei IA, et al. Among authors: kondrashov as. Nat Methods. 2010 Apr;7(4):248-9. doi: 10.1038/nmeth0410-248. Nat Methods. 2010. PMID: 20354512 Free PMC article. No abstract available.
A universal trend of amino acid gain and loss in protein evolution.
Jordan IK, Kondrashov FA, Adzhubei IA, Wolf YI, Koonin EV, Kondrashov AS, Sunyaev S. Jordan IK, et al. Among authors: kondrashov fa, kondrashov as. Nature. 2005 Feb 10;433(7026):633-8. doi: 10.1038/nature03306. Epub 2005 Jan 19. Nature. 2005. PMID: 15660107
Erratum.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: kondrashov fa, kondrashov as. PLoS Genet. 2008 Dec;4(12):10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. doi: 10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. Epub 2008 Dec 10. PLoS Genet. 2008. PMID: 19096535 Free PMC article.
Hypermutable non-synonymous sites are under stronger negative selection.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Adzuhbei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: kondrashov fa, kondrashov as. PLoS Genet. 2008 Nov;4(11):e1000281. doi: 10.1371/journal.pgen.1000281. Epub 2008 Nov 28. PLoS Genet. 2008. PMID: 19043566 Free PMC article.
Prediction of deleterious human alleles.
Sunyaev S, Ramensky V, Koch I, Lathe W 3rd, Kondrashov AS, Bork P. Sunyaev S, et al. Among authors: kondrashov as. Hum Mol Genet. 2001 Mar 15;10(6):591-7. doi: 10.1093/hmg/10.6.591. Hum Mol Genet. 2001. PMID: 11230178
Dobzhansky-Muller incompatibilities in protein evolution.
Kondrashov AS, Sunyaev S, Kondrashov FA. Kondrashov AS, et al. Among authors: kondrashov fa. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14878-83. doi: 10.1073/pnas.232565499. Epub 2002 Oct 28. Proc Natl Acad Sci U S A. 2002. PMID: 12403824 Free PMC article.
Negative selection in humans and fruit flies involves synergistic epistasis.
Sohail M, Vakhrusheva OA, Sul JH, Pulit SL, Francioli LC; Genome of the Netherlands Consortium; Alzheimer’s Disease Neuroimaging Initiative; van den Berg LH, Veldink JH, de Bakker PIW, Bazykin GA, Kondrashov AS, Sunyaev SR. Sohail M, et al. Among authors: kondrashov as. Science. 2017 May 5;356(6337):539-542. doi: 10.1126/science.aah5238. Science. 2017. PMID: 28473589 Free PMC article.
128 results