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Genome-wide association study of white-coat effect in hypertensive patients.
Rimpelä JM, Niiranen T, Jula A, Pörsti IH, Tikkakoski A, Havulinna A, Lehtimäki T, Salomaa V, Kontula KK, Hiltunen TP. Rimpelä JM, et al. Among authors: kontula kk. Blood Press. 2019 Aug;28(4):239-249. doi: 10.1080/08037051.2019.1604066. Epub 2019 May 2. Blood Press. 2019. PMID: 31044621
Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.
Salvi E, Wang Z, Rizzi F, Gong Y, McDonough CW, Padmanabhan S, Hiltunen TP, Lanzani C, Zaninello R, Chittani M, Bailey KR, Sarin AP, Barcella M, Melander O, Chapman AB, Manunta P, Kontula KK, Glorioso N, Cusi D, Dominiczak AF, Johnson JA, Barlassina C, Boerwinkle E, Cooper-DeHoff RM, Turner ST. Salvi E, et al. Among authors: kontula kk. Hypertension. 2017 Jan;69(1):51-59. doi: 10.1161/HYPERTENSIONAHA.116.08267. Epub 2016 Oct 31. Hypertension. 2017. PMID: 27802415 Free PMC article. Review.
Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design.
Nuotio ML, Sánez Tähtisalo H, Lahtinen A, Donner K, Fyhrquist F, Perola M, Kontula KK, Hiltunen TP. Nuotio ML, et al. Among authors: kontula kk. Epigenetics. 2022 Nov;17(11):1432-1445. doi: 10.1080/15592294.2022.2038418. Epub 2022 Feb 25. Epigenetics. 2022. PMID: 35213289 Free PMC article. Clinical Trial.
A common variant near the KCNJ2 gene is associated with T-peak to T-end interval.
Marjamaa A, Oikarinen L, Porthan K, Ripatti S, Peloso G, Noseworthy PA, Viitasalo M, Nieminen MS, Toivonen L, Kontula K, Peltonen L, Havulinna AS, Jula A, O'Donnell CJ, Newton-Cheh C, Perola M, Salomaa V. Marjamaa A, et al. Heart Rhythm. 2012 Jul;9(7):1099-103. doi: 10.1016/j.hrthm.2012.02.019. Epub 2012 Feb 15. Heart Rhythm. 2012. PMID: 22342860 Free PMC article.
324 results