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191 results

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Page 1
Showing results for ktp me
Search for Kop ME instead (1 results)
Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities.
Migliavacca E, Tay SKH, Patel HP, Sonntag T, Civiletto G, McFarlane C, Forrester T, Barton SJ, Leow MK, Antoun E, Charpagne A, Seng Chong Y, Descombes P, Feng L, Francis-Emmanuel P, Garratt ES, Giner MP, Green CO, Karaz S, Kothandaraman N, Marquis J, Metairon S, Moco S, Nelson G, Ngo S, Pleasants T, Raymond F, Sayer AA, Ming Sim C, Slater-Jefferies J, Syddall HE, Fang Tan P, Titcombe P, Vaz C, Westbury LD, Wong G, Yonghui W, Cooper C, Sheppard A, Godfrey KM, Lillycrop KA, Karnani N, Feige JN. Migliavacca E, et al. Nat Commun. 2019 Dec 20;10(1):5808. doi: 10.1038/s41467-019-13694-1. Nat Commun. 2019. PMID: 31862890 Free PMC article.
We provide an integrated molecular profile of human sarcopenia across ethnicities, demonstrating a fundamental role of altered mitochondrial metabolism in the pathological loss of skeletal muscle mass and function in older people....
We provide an integrated molecular profile of human sarcopenia across ethnicities, demonstrating a fundamental role of altered mitochondrial …
Proteome-Wide Characterizations of N6-Methyl-Adenosine Triphosphate- and N6-Furfuryl-Adenosine Triphosphate-Binding Capabilities of Kinases.
Dong X, Sun J, Miao W, Chang CA, Wang Y. Dong X, et al. Anal Chem. 2021 Oct 5;93(39):13251-13259. doi: 10.1021/acs.analchem.1c02565. Epub 2021 Sep 22. Anal Chem. 2021. PMID: 34549933 Free PMC article.
Herein, we employed isotope-coded ATP acyl-phosphate probes, in conjunction with a multiple-reaction monitoring (MRM)-based targeted proteomic method for proteome-wide identifications of endogenous kinases that can bind to two N(6)-modified ATP derivatives, N(6)-methyl-ATP (N(6)- …
Herein, we employed isotope-coded ATP acyl-phosphate probes, in conjunction with a multiple-reaction monitoring (MRM)-based targeted proteom …
Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia.
Membrez M, Migliavacca E, Christen S, Yaku K, Trieu J, Lee AK, Morandini F, Giner MP, Stiner J, Makarov MV, Garratt ES, Vasiloglou MF, Chanvillard L, Dalbram E, Ehrlich AM, Sanchez-Garcia JL, Canto C, Karagounis LG, Treebak JT, Migaud ME, Heshmat R, Razi F, Karnani N, Ostovar A, Farzadfar F, Tay SKH, Sanders MJ, Lillycrop KA, Godfrey KM, Nakagawa T, Moco S, Koopman R, Lynch GS, Sorrentino V, Feige JN. Membrez M, et al. Nat Metab. 2024 Mar;6(3):433-447. doi: 10.1038/s42255-024-00997-x. Epub 2024 Mar 19. Nat Metab. 2024. PMID: 38504132 Free PMC article.
Interaction of PINK1 with nucleotides and kinetin.
Gan ZY, Callegari S, Nguyen TN, Kirk NS, Leis A, Lazarou M, Dewson G, Komander D. Gan ZY, et al. Sci Adv. 2024 Jan 19;10(3):eadj7408. doi: 10.1126/sciadv.adj7408. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241364 Free PMC article.
The ubiquitin kinase PINK1 accumulates on damaged mitochondria to trigger mitophagy, and PINK1 loss-of-function mutations cause early onset Parkinson's disease. Nucleotide analogs such as kinetin triphosphate (KTP) were reported to enhance PINK1 activity and may represent …
The ubiquitin kinase PINK1 accumulates on damaged mitochondria to trigger mitophagy, and PINK1 loss-of-function mutations cause early onset …
Introduction to Pediatric Sleep Medicine.
Ramamurthy MB, Jayaprakash S. Ramamurthy MB, et al. Indian J Pediatr. 2023 Sep;90(9):927-933. doi: 10.1007/s12098-023-04697-4. Epub 2023 Jun 28. Indian J Pediatr. 2023. PMID: 37378884 Review.
In fact, sleep has been implicated in the optimal functioning of all organ systems - brain, heart, lung, metabolism, immune function, and hormonal balance too. One of the most common reasons for poor-quality sleep in children is a group of conditions termed sleep disordere …
In fact, sleep has been implicated in the optimal functioning of all organ systems - brain, heart, lung, metabolism, immune function, …
Digital transformation of mental health services.
Bond RR, Mulvenna MD, Potts C, O'Neill S, Ennis E, Torous J. Bond RR, et al. Npj Ment Health Res. 2023 Aug 22;2(1):13. doi: 10.1038/s44184-023-00033-y. Npj Ment Health Res. 2023. PMID: 38609479 Free PMC article. Review.
Pharmacogenomics in acute lymphoblastic leukemia.
Lee SHR, Yang JJ. Lee SHR, et al. Best Pract Res Clin Haematol. 2017 Sep;30(3):229-236. doi: 10.1016/j.beha.2017.07.007. Epub 2017 Jul 27. Best Pract Res Clin Haematol. 2017. PMID: 29050696 Review.
Renal vascular thrombosis in the newborn.
Resontoc LP, Yap HK. Resontoc LP, et al. Pediatr Nephrol. 2016 Jun;31(6):907-15. doi: 10.1007/s00467-015-3160-0. Epub 2015 Jul 15. Pediatr Nephrol. 2016. PMID: 26173707 Review.
191 results