Kosciuczuk E - Search Results

1

Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line.

Ardelt A, Carpenter R, Iwuchukwu I, Zhang A, Lin W, Kosciuczuk E, Hinkson C, Rebeiz T, Reitz S, King P. Ardelt A, et al. Among authors: kosciuczuk e. Data Brief. 2017 Oct 17;16:1083-1090. doi: 10.1016/j.dib.2017.10.033. eCollection 2018 Feb. Data Brief. 2017. PMID: 29854897 Free PMC article.

2

Transgenic expression of HuR increases vasogenic edema and impedes functional recovery in rodent ischemic stroke.

Ardelt AA, Carpenter RS, Iwuchukwu I, Zhang A, Lin W, Kosciuczuk E, Hinkson C, Rebeiz T, Reitz S, King PH. Ardelt AA, et al. Among authors: kosciuczuk e. Neurosci Lett. 2017 Nov 20;661:126-131. doi: 10.1016/j.neulet.2017.09.062. Epub 2017 Oct 2. Neurosci Lett. 2017. PMID: 28982595 Free PMC article.

3

Dual targeting of eIF4E by blocking MNK and mTOR pathways in leukemia.

Kosciuczuk EM, Saleiro D, Platanias LC. Kosciuczuk EM, et al. Cytokine. 2017 Jan;89:116-121. doi: 10.1016/j.cyto.2016.01.024. Epub 2016 Apr 16. Cytokine. 2017. PMID: 27094611 Free PMC article. Review.

4

Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors.

Wu EJ, Goussetis DJ, Beauchamp E, Kosciuczuk EM, Altman JK, Eklund EA, Platanias LC. Wu EJ, et al. Among authors: kosciuczuk em. Cancer Biol Ther. 2014 Apr;15(4):473-8. doi: 10.4161/cbt.27824. Epub 2014 Feb 4. Cancer Biol Ther. 2014. PMID: 24496081 Free PMC article.

5

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.

Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC. Kosciuczuk EM, et al. Blood. 2016 Jul 21;128(3):410-4. doi: 10.1182/blood-2016-02-698704. Epub 2016 Jun 15. Blood. 2016. PMID: 27307295 Free PMC article.

6

Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.

Beauchamp EM, Kosciuczuk EM, Serrano R, Nanavati D, Swindell EP, Viollet B, O'Halloran TV, Altman JK, Platanias LC. Beauchamp EM, et al. Mol Cancer Ther. 2015 Jan;14(1):202-12. doi: 10.1158/1535-7163.MCT-14-0665-T. Epub 2014 Oct 24. Mol Cancer Ther. 2015. PMID: 25344585 Free PMC article.

7

Central role of ULK1 in type I interferon signaling.

Saleiro D, Mehrotra S, Kroczynska B, Beauchamp EM, Lisowski P, Majchrzak-Kita B, Bhagat TD, Stein BL, McMahon B, Altman JK, Kosciuczuk EM, Baker DP, Jie C, Jafari N, Thompson CB, Levine RL, Fish EN, Verma AK, Platanias LC. Saleiro D, et al. Cell Rep. 2015 Apr 28;11(4):605-17. doi: 10.1016/j.celrep.2015.03.056. Epub 2015 Apr 16. Cell Rep. 2015. PMID: 25892232 Free PMC article.

8

Potent Antineoplastic Effects of Combined PI3Kα-MNK Inhibition in Medulloblastoma.

Eckerdt F, Bell JB, Beauchamp EM, Clymer J, Blyth GT, Kosciuczuk EM, Ma Q, Chen DZ, Horbinski C, Goldman S, Munshi HG, Hashizume R, Platanias LC. Eckerdt F, et al. Mol Cancer Res. 2019 Jun;17(6):1305-1315. doi: 10.1158/1541-7786.MCR-18-1193. Epub 2019 Mar 6. Mol Cancer Res. 2019. PMID: 30842251 Free PMC article.

9

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening.

Mishra RK, Clutter MR, Blyth GT, Kosciuczuk EM, Blackburn AZ, Beauchamp EM, Schiltz GE, Platanias LC. Mishra RK, et al. Among authors: kosciuczuk em. Chem Biol Drug Des. 2019 Oct;94(4):1813-1823. doi: 10.1111/cbdd.13585. Epub 2019 Aug 4. Chem Biol Drug Des. 2019. PMID: 31260185 Free PMC article.

10

Inhibitory effects of SEL201 in acute myeloid leukemia.

Kosciuczuk EM, Kar AK, Blyth GT, Fischietti M, Abedin S, Mina AA, Siliezar R, Rzymski T, Brzozka K, Eklund EA, Beauchamp EM, Eckerdt F, Saleiro D, Platanias LC. Kosciuczuk EM, et al. Oncotarget. 2019 Dec 24;10(67):7112-7121. doi: 10.18632/oncotarget.27388. eCollection 2019 Dec 24. Oncotarget. 2019. PMID: 31903169 Free PMC article.

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