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Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.
Nykänen AI, Sandelin H, Krebs R, Keränen MA, Tuuminen R, Kärpänen T, Wu Y, Pytowski B, Koskinen PK, Ylä-Herttuala S, Alitalo K, Lemström KB. Nykänen AI, et al. Among authors: koskinen pk. Circulation. 2010 Mar 30;121(12):1413-22. doi: 10.1161/CIRCULATIONAHA.109.910703. Epub 2010 Mar 15. Circulation. 2010. PMID: 20231530
Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis.
Lemström KB, Krebs R, Nykänen AI, Tikkanen JM, Sihvola RK, Aaltola EM, Häyry PJ, Wood J, Alitalo K, Ylä-Herttuala S, Koskinen PK. Lemström KB, et al. Among authors: koskinen pk. Circulation. 2002 May 28;105(21):2524-30. doi: 10.1161/01.cir.0000016821.76177.d2. Circulation. 2002. PMID: 12034660
Angiogenic growth factors in cardiac allograft rejection.
Nykänen AI, Tikkanen JM, Krebs R, Keränen MA, Sihvola RK, Sandelin H, Tuuminen R, Raisky O, Koskinen PK, Lemström KB. Nykänen AI, et al. Among authors: koskinen pk. Transplantation. 2006 Jul 15;82(1 Suppl):S22-4. doi: 10.1097/01.tp.0000231443.12570.57. Transplantation. 2006. PMID: 16829789 Review.
VEGFR-1 and -2 regulate inflammation, myocardial angiogenesis, and arteriosclerosis in chronically rejecting cardiac allografts.
Raisky O, Nykänen AI, Krebs R, Hollmén M, Keränen MA, Tikkanen JM, Sihvola R, Alhonen L, Salven P, Wu Y, Hicklin DJ, Alitalo K, Koskinen PK, Lemström KB. Raisky O, et al. Among authors: koskinen pk. Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):819-25. doi: 10.1161/01.ATV.0000260001.55955.6c. Epub 2007 Feb 8. Arterioscler Thromb Vasc Biol. 2007. PMID: 17290032
Vascular endothelial growth factor in chronic rat allograft nephropathy.
Malmström NK, Kallio EA, Rintala JM, Nykänen AI, Räisänen-Sokolowski AK, Paavonen T, Lemström KB, Koskinen PK. Malmström NK, et al. Among authors: koskinen pk. Transpl Immunol. 2008 May;19(2):136-44. doi: 10.1016/j.trim.2008.01.009. Epub 2008 Mar 3. Transpl Immunol. 2008. PMID: 18503889
100 results