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Instability restricts signaling of multiple fibroblast growth factors.
Buchtova M, Chaloupkova R, Zakrzewska M, Vesela I, Cela P, Barathova J, Gudernova I, Zajickova R, Trantirek L, Martin J, Kostas M, Otlewski J, Damborsky J, Kozubik A, Wiedlocha A, Krejci P. Buchtova M, et al. Among authors: kostas m. Cell Mol Life Sci. 2015 Jun;72(12):2445-59. doi: 10.1007/s00018-015-1856-8. Epub 2015 Feb 18. Cell Mol Life Sci. 2015. PMID: 25854632
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors.
Kostas M, Haugsten EM, Zhen Y, Sørensen V, Szybowska P, Fiorito E, Lorenz S, Jones N, de Souza GA, Wiedlocha A, Wesche J. Kostas M, et al. Mol Cell Proteomics. 2018 May;17(5):850-870. doi: 10.1074/mcp.RA117.000538. Epub 2018 Jan 25. Mol Cell Proteomics. 2018. PMID: 29371290 Free PMC article.
The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.
Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P. Fafilek B, et al. Among authors: kostas m. Sci Signal. 2018 Sep 18;11(548):eaap8608. doi: 10.1126/scisignal.aap8608. Sci Signal. 2018. PMID: 30228226
11 results