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A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase.
Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):E6020-E6029. doi: 10.1073/pnas.1806774115. Epub 2018 Jun 13.
Proc Natl Acad Sci U S A. 2018.
PMID: 29899144
Free PMC article.
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding.
Mysling S, Kristensen KK, Larsson M, Kovrov O, Bensadouen A, Jørgensen TJ, Olivecrona G, Young SG, Ploug M.
Mysling S, et al. Among authors: kovrov o.
Elife. 2016 Dec 8;5:e20958. doi: 10.7554/eLife.20958.
Elife. 2016.
PMID: 27929370
Free PMC article.
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On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity.
Kovrov O, Kristensen KK, Larsson E, Ploug M, Olivecrona G.
Kovrov O, et al.
J Lipid Res. 2019 Apr;60(4):783-793. doi: 10.1194/jlr.M088807. Epub 2019 Jan 27.
J Lipid Res. 2019.
PMID: 30686789
Free PMC article.
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Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1).
Reimund M, Larsson M, Kovrov O, Kasvandik S, Olivecrona G, Lookene A.
Reimund M, et al. Among authors: kovrov o.
J Biol Chem. 2015 May 29;290(22):13919-34. doi: 10.1074/jbc.M114.634626. Epub 2015 Apr 14.
J Biol Chem. 2015.
PMID: 25873395
Free PMC article.
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Lipoprotein lipase activity and interactions studied in human plasma by isothermal titration calorimetry.
Reimund M, Kovrov O, Olivecrona G, Lookene A.
Reimund M, et al. Among authors: kovrov o.
J Lipid Res. 2017 Jan;58(1):279-288. doi: 10.1194/jlr.D071787. Epub 2016 Nov 14.
J Lipid Res. 2017.
PMID: 27845686
Free PMC article.
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Lipoprotein size is a main determinant for the rate of hydrolysis by exogenous LPL in human plasma.
Kovrov O, Landfors F, Saar-Kovrov V, Näslund U, Olivecrona G.
Kovrov O, et al.
J Lipid Res. 2022 Jan;63(1):100144. doi: 10.1016/j.jlr.2021.100144. Epub 2021 Oct 26.
J Lipid Res. 2022.
PMID: 34710432
Free PMC article.
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D25V apolipoprotein C-III variant causes dominant hereditary systemic amyloidosis and confers cardiovascular protective lipoprotein profile.
Valleix S, Verona G, Jourde-Chiche N, Nédelec B, Mangione PP, Bridoux F, Mangé A, Dogan A, Goujon JM, Lhomme M, Dauteuille C, Chabert M, Porcari R, Waudby CA, Relini A, Talmud PJ, Kovrov O, Olivecrona G, Stoppini M, Christodoulou J, Hawkins PN, Grateau G, Delpech M, Kontush A, Gillmore JD, Kalopissis AD, Bellotti V.
Valleix S, et al. Among authors: kovrov o.
Nat Commun. 2016 Jan 21;7:10353. doi: 10.1038/ncomms10353.
Nat Commun. 2016.
PMID: 26790392
Free PMC article.
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