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Genome-wide association study of inhaled corticosteroid response in admixed children with asthma.
Hernandez-Pacheco N, Farzan N, Francis B, Karimi L, Repnik K, Vijverberg SJ, Soares P, Schieck M, Gorenjak M, Forno E, Eng C, Oh SS, Pérez-Méndez L, Berce V, Tavendale R, Samedy LA, Hunstman S, Hu D, Meade K, Farber HJ, Avila PC, Serebrisky D, Thyne SM, Brigino-Buenaventura E, Rodriguez-Cintron W, Sen S, Kumar R, Lenoir M, Rodriguez-Santana JR, Celedón JC, Mukhopadhyay S, Potočnik U, Pirmohamed M, Verhamme KM, Kabesch M, Palmer CNA, Hawcutt DB, Flores C, Maitland-van der Zee AH, Burchard EG, Pino-Yanes M. Hernandez-Pacheco N, et al. Among authors: kumar r. Clin Exp Allergy. 2019 Jun;49(6):789-798. doi: 10.1111/cea.13354. Epub 2019 Feb 15. Clin Exp Allergy. 2019. PMID: 30697902 Free PMC article. Clinical Trial.
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R. Seibold MA, et al. Among authors: kumar g, kumar r. Hum Mol Genet. 2008 Sep 1;17(17):2681-90. doi: 10.1093/hmg/ddn168. Epub 2008 Jun 4. Hum Mol Genet. 2008. PMID: 18535015 Free PMC article.
Food allergy is associated with an increased risk of asthma.
Schroeder A, Kumar R, Pongracic JA, Sullivan CL, Caruso DM, Costello J, Meyer KE, Vucic Y, Gupta R, Kim JS, Fuleihan R, Wang X. Schroeder A, et al. Among authors: kumar r. Clin Exp Allergy. 2009 Feb;39(2):261-70. doi: 10.1111/j.1365-2222.2008.03160.x. Clin Exp Allergy. 2009. PMID: 19187334 Free PMC article.
Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein.
Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG. Seibold MA, et al. Among authors: kumar r. J Biol Chem. 2009 Jul 17;284(29):19650-8. doi: 10.1074/jbc.M109.012443. Epub 2009 May 12. J Biol Chem. 2009. PMID: 19435888 Free PMC article.
Genetic ancestry in lung-function predictions.
Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara E, Meibohm B, Kritchevsky SB, Li R, Harris TB, Nickerson DA, Fornage M, Enright P, Ziv E, Smith LJ, Liu K, Burchard EG. Kumar R, et al. N Engl J Med. 2010 Jul 22;363(4):321-30. doi: 10.1056/NEJMoa0907897. Epub 2010 Jul 7. N Engl J Med. 2010. PMID: 20647190 Free PMC article.
Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.
Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir M, Rodríguez-Cintrón W, Avila PC, Lanfear DE, Burchard EG, Williams LK. Jin Y, et al. Among authors: kumar r. J Allergy Clin Immunol. 2010 Sep;126(3):618-25.e1-2. doi: 10.1016/j.jaci.2010.06.007. Epub 2010 Jul 31. J Allergy Clin Immunol. 2010. PMID: 20673984 Free PMC article. Clinical Trial.
Factors predicting inhaled corticosteroid responsiveness in African American patients with asthma.
Gould W, Peterson EL, Karungi G, Zoratti A, Gaggin J, Toma G, Yan S, Levin AM, Yang JJ, Wells K, Wang M, Burke RR, Beckman K, Popadic D, Land SJ, Kumar R, Seibold MA, Lanfear DE, Burchard EG, Williams LK. Gould W, et al. Among authors: kumar r. J Allergy Clin Immunol. 2010 Dec;126(6):1131-8. doi: 10.1016/j.jaci.2010.08.002. J Allergy Clin Immunol. 2010. PMID: 20864153 Free PMC article.
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