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Page 1
Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.
van Laarhoven A, Dian S, Aguirre-Gamboa R, Avila-Pacheco J, Ricaño-Ponce I, Ruesen C, Annisa J, Koeken VACM, Chaidir L, Li Y, Achmad TH, Joosten LAB, Notebaart RA, Ruslami R, Netea MG, Verbeek MM, Alisjahbana B, Kumar V, Clish CB, Ganiem AR, van Crevel R. van Laarhoven A, et al. Among authors: kumar v. Lancet Infect Dis. 2018 May;18(5):526-535. doi: 10.1016/S1473-3099(18)30053-7. Epub 2018 Feb 3. Lancet Infect Dis. 2018. PMID: 29395996
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.
Smeekens SP, Ng A, Kumar V, Johnson MD, Plantinga TS, van Diemen C, Arts P, Verwiel ET, Gresnigt MS, Fransen K, van Sommeren S, Oosting M, Cheng SC, Joosten LA, Hoischen A, Kullberg BJ, Scott WK, Perfect JR, van der Meer JW, Wijmenga C, Netea MG, Xavier RJ. Smeekens SP, et al. Among authors: kumar v. Nat Commun. 2013;4:1342. doi: 10.1038/ncomms2343. Nat Commun. 2013. PMID: 23299892 Free PMC article.
Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant.
Almeida R, Ricaño-Ponce I, Kumar V, Deelen P, Szperl A, Trynka G, Gutierrez-Achury J, Kanterakis A, Westra HJ, Franke L, Swertz MA, Platteel M, Bilbao JR, Barisani D, Greco L, Mearin L, Wolters VM, Mulder C, Mazzilli MC, Sood A, Cukrowska B, Núñez C, Pratesi R, Withoff S, Wijmenga C. Almeida R, et al. Among authors: kumar v. Hum Mol Genet. 2014 May 1;23(9):2481-9. doi: 10.1093/hmg/ddt619. Epub 2013 Dec 11. Hum Mol Genet. 2014. PMID: 24334606 Free PMC article.
Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels.
Kumar V, Gutierrez-Achury J, Kanduri K, Almeida R, Hrdlickova B, Zhernakova DV, Westra HJ, Karjalainen J, Ricaño-Ponce I, Li Y, Stachurska A, Tigchelaar EF, Abdulahad WH, Lähdesmäki H, Hofker MH, Zhernakova A, Franke L, Lahesmaa R, Wijmenga C, Withoff S. Kumar V, et al. Hum Mol Genet. 2015 Jan 15;24(2):397-409. doi: 10.1093/hmg/ddu453. Epub 2014 Sep 4. Hum Mol Genet. 2015. PMID: 25190711
Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia.
Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JWM, Joosten LAB, Bochud PY, Marchetti O, Perfect JR, Xavier R, Kullberg BJ, Wijmenga C, Netea MG. Kumar V, et al. Nat Commun. 2014 Sep 8;5:4675. doi: 10.1038/ncomms5675. Nat Commun. 2014. PMID: 25197941 Free PMC article.
mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.
Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG. Cheng SC, et al. Among authors: kumar v. Science. 2014 Sep 26;345(6204):1250684. doi: 10.1126/science.1250684. Science. 2014. PMID: 25258083 Free PMC article.
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.
Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, Cheng SC, Ratter J, Berentsen K, van der Ent MA, Sharifi N, Janssen-Megens EM, Ter Huurne M, Mandoli A, van Schaik T, Ng A, Burden F, Downes K, Frontini M, Kumar V, Giamarellos-Bourboulis EJ, Ouwehand WH, van der Meer JW, Joosten LA, Wijmenga C, Martens JH, Xavier RJ, Logie C, Netea MG, Stunnenberg HG. Saeed S, et al. Among authors: kumar v. Science. 2014 Sep 26;345(6204):1251086. doi: 10.1126/science.1251086. Science. 2014. PMID: 25258085 Free PMC article.
Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.
Buffen K, Oosting M, Quintin J, Ng A, Kleinnijenhuis J, Kumar V, van de Vosse E, Wijmenga C, van Crevel R, Oosterwijk E, Grotenhuis AJ, Vermeulen SH, Kiemeney LA, van de Veerdonk FL, Chamilos G, Xavier RJ, van der Meer JW, Netea MG, Joosten LA. Buffen K, et al. Among authors: kumar v. PLoS Pathog. 2014 Oct 30;10(10):e1004485. doi: 10.1371/journal.ppat.1004485. eCollection 2014 Oct. PLoS Pathog. 2014. PMID: 25356988 Free PMC article.
The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections.
Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. Jaeger M, et al. Among authors: kumar v. Eur J Clin Microbiol Infect Dis. 2015 May;34(5):963-974. doi: 10.1007/s10096-014-2309-2. Epub 2015 Jan 13. Eur J Clin Microbiol Infect Dis. 2015. PMID: 25579795 Free PMC article.
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.
Begun J, Lassen KG, Jijon HB, Baxt LA, Goel G, Heath RJ, Ng A, Tam JM, Kuo SY, Villablanca EJ, Fagbami L, Oosting M, Kumar V, Schenone M, Carr SA, Joosten LA, Vyas JM, Daly MJ, Netea MG, Brown GD, Wijmenga C, Xavier RJ. Begun J, et al. Among authors: kumar v. Cell Rep. 2015 Jun 30;11(12):1905-18. doi: 10.1016/j.celrep.2015.05.045. Epub 2015 Jun 18. Cell Rep. 2015. PMID: 26095365 Free PMC article.
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