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Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.
Schafmayer C, Harrison JW, Buch S, Lange C, Reichert MC, Hofer P, Cossais F, Kupcinskas J, von Schönfels W, Schniewind B, Kruis W, Tepel J, Zobel M, Rosendahl J, Jacobi T, Walther-Berends A, Schroeder M, Vogel I, Sergeev P, Boedeker H, Hinrichsen H, Volk A, Erk JU, Burmeister G, Hendricks A, Hinz S, Wolff S, Böttner M, Wood AR, Tyrrell J, Beaumont RN, Langheinrich M, Kucharzik T, Brezina S, Huber-Schönauer U, Pietsch L, Noack LS, Brosch M, Herrmann A, Thangapandi RV, Schimming HW, Zeissig S, Palm S, Focke G, Andreasson A, Schmidt PT, Weitz J, Krawczak M, Völzke H, Leeb G, Michl P, Lieb W, Grützmann R, Franke A, Lammert F, Becker T, Kupcinskas L, D'Amato M, Wedel T, Datz C, Gsur A, Weedon MN, Hampe J. Schafmayer C, et al. Among authors: kupcinskas j, kupcinskas l. Gut. 2019 May;68(5):854-865. doi: 10.1136/gutjnl-2018-317619. Epub 2019 Jan 19. Gut. 2019. PMID: 30661054
Common variation in FAM155A is associated with diverticulitis but not diverticulosis.
Reichert MC, Kupcinskas J, Schulz A, Schramm C, Weber SN, Krawczyk M, Jüngst C, Casper M, Grünhage F, Appenrodt B, Zimmer V, Tamelis A, Lukosiene JI, Pauziene N, Kiudelis G, Jonaitis L, Goeser T, Malinowski M, Glanemann M, Kupcinskas L, Lammert F. Reichert MC, et al. Among authors: kupcinskas j, kupcinskas l. Sci Rep. 2020 Feb 3;10(1):1658. doi: 10.1038/s41598-020-58437-1. Sci Rep. 2020. PMID: 32015353 Free PMC article.
PNPLA3 and RNF7 Gene Variants are Associated with the Risk of Developing Liver Fibrosis and Cirrhosis in an Eastern European Population.
Kupcinskas J, Valantiene I, Varkalaitė G, Steponaitiene R, Skieceviciene J, Sumskiene J, Petrenkiene V, Kondrackiene J, Kiudelis G, Lammert F, Kupcinskas L. Kupcinskas J, et al. Among authors: kupcinskas l. J Gastrointestin Liver Dis. 2017 Mar;26(1):37-43. doi: 10.15403/jgld.2014.1121.261.pnp. J Gastrointestin Liver Dis. 2017. PMID: 28338112 Free article.
Molecular Alterations in Gastric Intestinal Metaplasia.
Jonaitis P, Kupcinskas L, Kupcinskas J. Jonaitis P, et al. Among authors: kupcinskas j, kupcinskas l. Int J Mol Sci. 2021 May 28;22(11):5758. doi: 10.3390/ijms22115758. Int J Mol Sci. 2021. PMID: 34071181 Free PMC article. Review.
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).
Franke A, Balschun T, Sina C, Ellinghaus D, Häsler R, Mayr G, Albrecht M, Wittig M, Buchert E, Nikolaus S, Gieger C, Wichmann HE, Sventoraityte J, Kupcinskas L, Onnie CM, Gazouli M, Anagnou NP, Strachan D, McArdle WL, Mathew CG, Rutgeerts P, Vermeire S, Vatn MH; IBSEN study group; Krawczak M, Rosenstiel P, Karlsen TH, Schreiber S. Franke A, et al. Among authors: kupcinskas l. Nat Genet. 2010 Apr;42(4):292-4. doi: 10.1038/ng.553. Epub 2010 Mar 14. Nat Genet. 2010. PMID: 20228798
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies.
Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Häsler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V, Vogel U, Kupcinskas L, Kayser M, Krawczak M, Nikolaus S, Weersma RK, Ponsioen CY, Sans M, Wijmenga C, Strachan DP, McArdle WL, Vermeire S, Rutgeerts P, Sanderson JD, Mathew CG, Vatn MH, Wang J, Nöthen MM, Duerr RH, Büning C, Brand S, Glas J, Winkelmann J, Illig T, Latiano A, Annese V, Halfvarson J, D'Amato M, Daly MJ, Nothnagel M, Karlsen TH, Subramani S, Rosenstiel P, Schreiber S, Parkes M, Franke A. Ellinghaus D, et al. Among authors: kupcinskas l. Gastroenterology. 2013 Aug;145(2):339-47. doi: 10.1053/j.gastro.2013.04.040. Epub 2013 Apr 25. Gastroenterology. 2013. PMID: 23624108 Free PMC article.
A Variant of COL3A1 (rs3134646) Is Associated With Risk of Developing Diverticulosis in White Men.
Reichert MC, Kupcinskas J, Krawczyk M, Jüngst C, Casper M, Grünhage F, Appenrodt B, Zimmer V, Weber SN, Tamelis A, Lukosiene JI, Pauziene N, Kiudelis G, Jonaitis L, Schramm C, Goeser T, Schulz A, Malinowski M, Glanemann M, Kupcinskas L, Lammert F. Reichert MC, et al. Among authors: kupcinskas j, kupcinskas l. Dis Colon Rectum. 2018 May;61(5):604-611. doi: 10.1097/DCR.0000000000001001. Dis Colon Rectum. 2018. PMID: 29533249
182 results