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Page 1
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy.
Drießen S, Berleth N, Friesen O, Löffler AS, Böhler P, Hieke N, Stuhldreier F, Peter C, Schink KO, Schultz SW, Stenmark H, Holland P, Simonsen A, Wesselborg S, Stork B. Drießen S, et al. Among authors: loffler as. Autophagy. 2015;11(9):1458-70. doi: 10.1080/15548627.2015.1067359. Autophagy. 2015. PMID: 26207339 Free PMC article.
Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells.
Hieke N, Löffler AS, Kaizuka T, Berleth N, Böhler P, Drießen S, Stuhldreier F, Friesen O, Assani K, Schmitz K, Peter C, Diedrich B, Dengjel J, Holland P, Simonsen A, Wesselborg S, Mizushima N, Stork B. Hieke N, et al. Among authors: loffler as. Autophagy. 2015;11(9):1471-83. doi: 10.1080/15548627.2015.1068488. Autophagy. 2015. PMID: 26213203 Free PMC article.
An essential role of the autophagy activating kinase ULK1 in snRNP biogenesis.
Schmitz K, Cox J, Esser LM, Voss M, Sander K, Löffler A, Hillebrand F, Erkelenz S, Schaal H, Kähne T, Klinker S, Zhang T, Nagel-Steger L, Willbold D, Seggewiß S, Schlütermann D, Stork B, Grimmler M, Wesselborg S, Peter C. Schmitz K, et al. Nucleic Acids Res. 2021 Jun 21;49(11):6437-6455. doi: 10.1093/nar/gkab452. Nucleic Acids Res. 2021. PMID: 34096600 Free PMC article.
Atg13 and FIP200 act independently of Ulk1 and Ulk2 in autophagy induction.
Alers S, Löffler AS, Paasch F, Dieterle AM, Keppeler H, Lauber K, Campbell DG, Fehrenbacher B, Schaller M, Wesselborg S, Stork B. Alers S, et al. Among authors: loffler as. Autophagy. 2011 Dec;7(12):1423-33. doi: 10.4161/auto.7.12.18027. Autophagy. 2011. PMID: 22024743 Free PMC article.
PDK1 controls upstream PI3K expression and PIP3 generation.
Dieterle AM, Böhler P, Keppeler H, Alers S, Berleth N, Drießen S, Hieke N, Pietkiewicz S, Löffler AS, Peter C, Gray A, Leslie NR, Shinohara H, Kurosaki T, Engelke M, Wienands J, Bonin M, Wesselborg S, Stork B. Dieterle AM, et al. Among authors: loffler as. Oncogene. 2014 Jun 5;33(23):3043-53. doi: 10.1038/onc.2013.266. Epub 2013 Jul 29. Oncogene. 2014. PMID: 23893244
The incredible ULKs.
Alers S, Löffler AS, Wesselborg S, Stork B. Alers S, et al. Among authors: loffler as. Cell Commun Signal. 2012 Mar 13;10(1):7. doi: 10.1186/1478-811X-10-7. Cell Commun Signal. 2012. PMID: 22413737 Free PMC article.
Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index.
Löffler A, Luck T, Then FS, Sikorski C, Kovacs P, Böttcher Y, Breitfeld J, Tönjes A, Horstmann A, Löffler M, Engel C, Thiery J, Villringer A, Stumvoll M, Riedel-Heller SG. Löffler A, et al. PLoS One. 2015 Jul 31;10(7):e0133977. doi: 10.1371/journal.pone.0133977. eCollection 2015. PLoS One. 2015. PMID: 26230264 Free PMC article.
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