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Page 1
Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.
Myers RW, Guan HP, Ehrhart J, Petrov A, Prahalada S, Tozzo E, Yang X, Kurtz MM, Trujillo M, Gonzalez Trotter D, Feng D, Xu S, Eiermann G, Holahan MA, Rubins D, Conarello S, Niu X, Souza SC, Miller C, Liu J, Lu K, Feng W, Li Y, Painter RE, Milligan JA, He H, Liu F, Ogawa A, Wisniewski D, Rohm RJ, Wang L, Bunzel M, Qian Y, Zhu W, Wang H, Bennet B, LaFranco Scheuch L, Fernandez GE, Li C, Klimas M, Zhou G, van Heek M, Biftu T, Weber A, Kelley DE, Thornberry N, Erion MD, Kemp DM, Sebhat IK. Myers RW, et al. Among authors: lafranco scheuch l. Science. 2017 Aug 4;357(6350):507-511. doi: 10.1126/science.aah5582. Epub 2017 Jul 13. Science. 2017. PMID: 28705990
Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity.
Li Y, Evers R, Hafey MJ, Cheon K, Duong H, Lynch D, LaFranco-Scheuch L, Pacchione S, Tamburino AM, Tanis KQ, Geddes K, Holder D, Zhang NR, Kang W, Gonzalez RJ, Galijatovic-Idrizbegovic A, Pearson KM, Lebron JA, Glaab WE, Sistare FD. Li Y, et al. Among authors: lafranco scheuch l. Toxicol Sci. 2019 Jul 1;170(1):180-198. doi: 10.1093/toxsci/kfz079. Toxicol Sci. 2019. PMID: 30903168
Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice.
Aslamkhan AG, Xu Q, Loughlin A, Vu H, Pacchione S, Bhatt B, Garfinkel I, Styring TG, LaFranco-Scheuch L, Pearson K, Reynolds S, Li N, Zhou H, Miller JR, Solban N, Bass A, Glaab WE. Aslamkhan AG, et al. Among authors: lafranco scheuch l. Toxicol Appl Pharmacol. 2020 Nov 1;406:115216. doi: 10.1016/j.taap.2020.115216. Epub 2020 Aug 29. Toxicol Appl Pharmacol. 2020. PMID: 32871117
Effects of LRRK2 Inhibitors in Nonhuman Primates.
Miller GK, Kuruvilla S, Jacob B, LaFranco-Scheuch L, Bakthavatchalu V, Flor J, Flor K, Ziegler J, Reichard C, Manfre P, Firner S, McNutt T, Quay D, Bellum S, Doto G, Ciaccio PJ, Pearson K, Valentine J, Fuller P, Fell M, Tsuchiya T, Williamson T, Wollenberg G. Miller GK, et al. Among authors: lafranco scheuch l. Toxicol Pathol. 2023 Jul;51(5):232-245. doi: 10.1177/01926233231205895. Epub 2023 Nov 2. Toxicol Pathol. 2023. PMID: 37916535
Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.
Methot JL, Zhou H, Kattar SD, McGowan MA, Wilson K, Garcia Y, Deng Y, Altman M, Fradera X, Lesburg C, Fischmann T, Li C, Alves S, Shah S, Fernandez R, Goldenblatt P, Hill A, Shaffer L, Chen D, Tong V, McLeod RL, Yu H, Bass A, Kemper R, Gatto NT, LaFranco-Scheuch L, Trotter BW, Guzi T, Katz JD. Methot JL, et al. Among authors: lafranco scheuch l. J Med Chem. 2019 May 9;62(9):4370-4382. doi: 10.1021/acs.jmedchem.8b01818. Epub 2019 Apr 22. J Med Chem. 2019. PMID: 30986068
Sneezing, nasal discharge, dyspnea and sudden death in rabbits.
Geertsema RS, LaFranco-Scheuch L, Jenné KJ, Richter PJ. Geertsema RS, et al. Among authors: lafranco scheuch l. Lab Anim (NY). 2008 Jan;37(1):17. doi: 10.1038/laban0108-17. Lab Anim (NY). 2008. PMID: 18094696 No abstract available.
Pulmonary coccidioidomycosis in a neonatal foal.
Maleski K, Magdesian KG, LaFranco-Scheuch L, Pappagianis D, Carlson GP. Maleski K, et al. Among authors: lafranco scheuch l. Vet Rec. 2002 Oct 26;151(17):505-8. doi: 10.1136/vr.151.17.505. Vet Rec. 2002. PMID: 12430999