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Co-regulatory networks of human serum proteins link genetics to disease.
Emilsson V, Ilkov M, Lamb JR, Finkel N, Gudmundsson EF, Pitts R, Hoover H, Gudmundsdottir V, Horman SR, Aspelund T, Shu L, Trifonov V, Sigurdsson S, Manolescu A, Zhu J, Olafsson Ö, Jakobsdottir J, Lesley SA, To J, Zhang J, Harris TB, Launer LJ, Zhang B, Eiriksdottir G, Yang X, Orth AP, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: lamb jr. Science. 2018 Aug 24;361(6404):769-773. doi: 10.1126/science.aaq1327. Epub 2018 Aug 2. Science. 2018. PMID: 30072576 Free PMC article.
Circulating Protein Signatures and Causal Candidates for Type 2 Diabetes.
Gudmundsdottir V, Zaghlool SB, Emilsson V, Aspelund T, Ilkov M, Gudmundsson EF, Jonsson SM, Zilhão NR, Lamb JR, Suhre K, Jennings LL, Gudnason V. Gudmundsdottir V, et al. Among authors: lamb jr. Diabetes. 2020 Aug;69(8):1843-1853. doi: 10.2337/db19-1070. Epub 2020 May 8. Diabetes. 2020. PMID: 32385057 Free PMC article.
It's in Our Blood: A Glimpse of Personalized Medicine.
Lamb JR, Jennings LL, Gudmundsdottir V, Gudnason V, Emilsson V. Lamb JR, et al. Trends Mol Med. 2021 Jan;27(1):20-30. doi: 10.1016/j.molmed.2020.09.003. Epub 2020 Sep 25. Trends Mol Med. 2021. PMID: 32988739 Review.
Coding and regulatory variants are associated with serum protein levels and disease.
Emilsson V, Gudmundsdottir V, Gudjonsson A, Jonmundsson T, Jonsson BG, Karim MA, Ilkov M, Staley JR, Gudmundsson EF, Launer LJ, Lindeman JH, Morton NM, Aspelund T, Lamb JR, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: lamb jr. Nat Commun. 2022 Jan 25;13(1):481. doi: 10.1038/s41467-022-28081-6. Nat Commun. 2022. PMID: 35079000 Free PMC article.
Serum levels of ACE2 are higher in patients with obesity and diabetes.
Emilsson V, Gudmundsson EF, Aspelund T, Jonsson BG, Gudjonsson A, Launer LJ, Lamb JR, Gudmundsdottir V, Jennings LL, Gudnason V. Emilsson V, et al. Among authors: lamb jr. Obes Sci Pract. 2020 Dec 16;7(2):239-243. doi: 10.1002/osp4.472. eCollection 2021 Apr. Obes Sci Pract. 2020. PMID: 33841894 Free PMC article.
A proteogenomic signature of age-related macular degeneration in blood.
Emilsson V, Gudmundsson EF, Jonmundsson T, Jonsson BG, Twarog M, Gudmundsdottir V, Li Z, Finkel N, Poor S, Liu X, Esterberg R, Zhang Y, Jose S, Huang CL, Liao SM, Loureiro J, Zhang Q, Grosskreutz CL, Nguyen AA, Huang Q, Leehy B, Pitts R, Aspelund T, Lamb JR, Jonasson F, Launer LJ, Cotch MF, Jennings LL, Gudnason V, Walshe TE. Emilsson V, et al. Among authors: lamb jr. Nat Commun. 2022 Jun 13;13(1):3401. doi: 10.1038/s41467-022-31085-x. Nat Commun. 2022. PMID: 35697682 Free PMC article.
Genetics of gene expression and its effect on disease.
Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, Jonasdottir A, Styrkarsdottir U, Gretarsdottir S, Magnusson KP, Stefansson H, Fossdal R, Kristjansson K, Gislason HG, Stefansson T, Leifsson BG, Thorsteinsdottir U, Lamb JR, Gulcher JR, Reitman ML, Kong A, Schadt EE, Stefansson K. Emilsson V, et al. Among authors: lamb jr. Nature. 2008 Mar 27;452(7186):423-8. doi: 10.1038/nature06758. Epub 2008 Mar 16. Nature. 2008. PMID: 18344981
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V. Zhang B, et al. Among authors: lamb jr. Cell. 2013 Apr 25;153(3):707-20. doi: 10.1016/j.cell.2013.03.030. Cell. 2013. PMID: 23622250 Free PMC article.
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases.
Narayanan M, Huynh JL, Wang K, Yang X, Yoo S, McElwee J, Zhang B, Zhang C, Lamb JR, Xie T, Suver C, Molony C, Melquist S, Johnson AD, Fan G, Stone DJ, Schadt EE, Casaccia P, Emilsson V, Zhu J. Narayanan M, et al. Among authors: lamb jr. Mol Syst Biol. 2014 Jul 30;10(7):743. doi: 10.15252/msb.20145304. Mol Syst Biol. 2014. PMID: 25080494 Free PMC article.
366 results