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TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease.
Ferreira RR, Abreu RDS, Vilar-Pereira G, Degrave W, Meuser-Batista M, Ferreira NVC, da Cruz Moreira O, da Silva Gomes NL, Mello de Souza E, Ramos IP, Bailly S, Feige JJ, Lannes-Vieira J, de Araújo-Jorge TC, Waghabi MC. Ferreira RR, et al. PLoS Negl Trop Dis. 2019 Jul 31;13(7):e0007602. doi: 10.1371/journal.pntd.0007602. eCollection 2019 Jul. PLoS Negl Trop Dis. 2019. PMID: 31365537 Free PMC article.
In vitro and in vivo experimental models for drug screening and development for Chagas disease.
Romanha AJ, Castro SL, Soeiro Mde N, Lannes-Vieira J, Ribeiro I, Talvani A, Bourdin B, Blum B, Olivieri B, Zani C, Spadafora C, Chiari E, Chatelain E, Chaves G, Calzada JE, Bustamante JM, Freitas-Junior LH, Romero LI, Bahia MT, Lotrowska M, Soares M, Andrade SG, Armstrong T, Degrave W, Andrade Zde A. Romanha AJ, et al. Mem Inst Oswaldo Cruz. 2010 Mar;105(2):233-8. doi: 10.1590/s0074-02762010000200022. Mem Inst Oswaldo Cruz. 2010. PMID: 20428688 Free article.
Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatment.
Batista Dda G, Batista MM, de Oliveira GM, do Amaral PB, Lannes-Vieira J, Britto CC, Junqueira A, Lima MM, Romanha AJ, Sales Junior PA, Stephens CE, Boykin DW, Soeiro Mde N. Batista Dda G, et al. Antimicrob Agents Chemother. 2010 Jul;54(7):2940-52. doi: 10.1128/AAC.01617-09. Epub 2010 May 10. Antimicrob Agents Chemother. 2010. PMID: 20457822 Free PMC article.
Mast cell function and death in Trypanosoma cruzi infection.
Meuser-Batista M, Corrêa JR, Carvalho VF, de Carvalho Britto CF, Moreira OC, Batista MM, Soares MJ, Filho FA, E Silva PM, Lannes-Vieira J, Silva RC, Henriques-Pons A. Meuser-Batista M, et al. Am J Pathol. 2011 Oct;179(4):1894-904. doi: 10.1016/j.ajpath.2011.06.014. Epub 2011 Aug 3. Am J Pathol. 2011. PMID: 21819958 Free PMC article.
Inducible nitric oxide synthase in heart tissue and nitric oxide in serum of Trypanosoma cruzi-infected rhesus monkeys: association with heart injury.
Carvalho CM, Silverio JC, da Silva AA, Pereira IR, Coelho JM, Britto CC, Moreira OC, Marchevsky RS, Xavier SS, Gazzinelli RT, da Glória Bonecini-Almeida M, Lannes-Vieira J. Carvalho CM, et al. PLoS Negl Trop Dis. 2012;6(5):e1644. doi: 10.1371/journal.pntd.0001644. Epub 2012 May 8. PLoS Negl Trop Dis. 2012. PMID: 22590660 Free PMC article.
107 results