Lappegård KT - Search Results

1

Therapeutic complement inhibition – from experimental to clinical medicine.

Lappegård KT, Bjerre A, Tjønnfjord GE, Mollnes TE. Lappegård KT, et al. Tidsskr Nor Laegeforen. 2015 Oct 20;135(19):1745-9. doi: 10.4045/tidsskr.15.0049. eCollection 2015 Oct 20. Tidsskr Nor Laegeforen. 2015. PMID: 26486669 Free article. Review. English, Norwegian.

2

LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response.

Lappegård KT, Enebakk T, Thunhaug H, Ludviksen JK, Mollnes TE, Hovland A. Lappegård KT, et al. J Clin Lipidol. 2016 Nov-Dec;10(6):1481-1487. doi: 10.1016/j.jacl.2016.09.001. Epub 2016 Sep 13. J Clin Lipidol. 2016. PMID: 27919366

3

A vital role for complement in heart disease.

Lappegård KT, Garred P, Jonasson L, Espevik T, Aukrust P, Yndestad A, Mollnes TE, Hovland A. Lappegård KT, et al. Mol Immunol. 2014 Oct;61(2):126-34. doi: 10.1016/j.molimm.2014.06.036. Epub 2014 Jul 16. Mol Immunol. 2014. PMID: 25037633 Free article. Review.

4

Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation.

Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Lambris JD, Videm V, Mollnes TE. Lappegård KT, et al. Ann Thorac Surg. 2004 Mar;77(3):932-41. doi: 10.1016/S0003-4975(03)01519-4. Ann Thorac Surg. 2004. PMID: 14992902

5

Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition.

Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Mollnes TE. Lappegård KT, et al. Ann Thorac Surg. 2004 Jul;78(1):38-44; discussion 44-5. doi: 10.1016/j.athoracsur.2004.02.005. Ann Thorac Surg. 2004. PMID: 15223398

6

Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production.

Lappegård KT, Riesenfeld J, Brekke OL, Bergseth G, Lambris JD, Mollnes TE. Lappegård KT, et al. Ann Thorac Surg. 2005 Mar;79(3):917-23. doi: 10.1016/j.athoracsur.2004.08.015. Ann Thorac Surg. 2005. PMID: 15734405

7

Role of granulocytes and monocytes in the polyvinyl chloride-induced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4.

Lappegård KT, Bergseth G, Riesenfeld J, Sexton J, Mollnes TE. Lappegård KT, et al. J Biomed Mater Res A. 2005 Aug 1;74(2):230-6. doi: 10.1002/jbm.a.30372. J Biomed Mater Res A. 2005. PMID: 15962266

8

Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person.

Bergseth G, Lambris JD, Mollnes TE, Lappegård KT. Bergseth G, et al. Among authors: lappegard kt. Ann Thorac Surg. 2011 Feb;91(2):527-33. doi: 10.1016/j.athoracsur.2010.10.084. Ann Thorac Surg. 2011. PMID: 21256307 Free PMC article.

9

Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature.

Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE. Lappegård KT, et al. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15861-6. doi: 10.1073/pnas.0903613106. Epub 2009 Aug 26. Proc Natl Acad Sci U S A. 2009. PMID: 19717455 Free PMC article.

10

Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies.

Hellerud BC, Aase A, Herstad TK, Naess LM, Kristiansen LH, Trøseid AM, Harboe M, Lappegård KT, Brandtzaeg P, Høiby EA, Mollnes TE. Hellerud BC, et al. Among authors: lappegard kt. Infect Immun. 2010 Feb;78(2):802-9. doi: 10.1128/IAI.01044-09. Epub 2009 Nov 23. Infect Immun. 2010. PMID: 19933829 Free PMC article.

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