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Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibility locus that shows a long-range interaction with the SLC16A1 gene.
Avitabile M, Succoio M, Testori A, Cardinale A, Vaksman Z, Lasorsa VA, Cantalupo S, Esposito M, Cimmino F, Montella A, Formicola D, Koster J, Andreotti V, Ghiorzo P, Romano MF, Staibano S, Scalvenzi M, Ayala F, Hakonarson H, Corrias MV, Devoto M, Law MH, Iles MM, Brown K, Diskin S, Zambrano N, Iolascon A, Capasso M. Avitabile M, et al. Among authors: lasorsa va. Carcinogenesis. 2020 May 14;41(3):284-295. doi: 10.1093/carcin/bgz153. Carcinogenesis. 2020. PMID: 31605138 Free PMC article.
Exome and deep sequencing of clinically aggressive neuroblastoma reveal somatic mutations that affect key pathways involved in cancer progression.
Lasorsa VA, Formicola D, Pignataro P, Cimmino F, Calabrese FM, Mora J, Esposito MR, Pantile M, Zanon C, De Mariano M, Longo L, Hogarty MD, de Torres C, Tonini GP, Iolascon A, Capasso M. Lasorsa VA, et al. Oncotarget. 2016 Apr 19;7(16):21840-52. doi: 10.18632/oncotarget.8187. Oncotarget. 2016. PMID: 27009842 Free PMC article.
BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma.
Sime W, Niu Q, Abassi Y, Masoumi KC, Zarrizi R, Køhler JB, Kjellström S, Lasorsa VA, Capasso M, Fu H, Massoumi R. Sime W, et al. Among authors: lasorsa va. Cell Death Dis. 2018 May 1;9(5):458. doi: 10.1038/s41419-018-0500-6. Cell Death Dis. 2018. PMID: 29686263 Free PMC article.
Somatic mutations in specific and connected subpathways are associated with short neuroblastoma patients' survival and indicate proteins targetable at onset of disease.
Esposito MR, Binatti A, Pantile M, Coppe A, Mazzocco K, Longo L, Capasso M, Lasorsa VA, Luksch R, Bortoluzzi S, Tonini GP. Esposito MR, et al. Among authors: lasorsa va. Int J Cancer. 2018 Nov 15;143(10):2525-2536. doi: 10.1002/ijc.31748. Epub 2018 Sep 17. Int J Cancer. 2018. PMID: 29992558 Free article.
HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia.
Cimmino F, Avitabile M, Lasorsa VA, Montella A, Pezone L, Cantalupo S, Visconte F, Corrias MV, Iolascon A, Capasso M. Cimmino F, et al. Among authors: lasorsa va. BMC Med Genet. 2019 Feb 26;20(1):37. doi: 10.1186/s12881-019-0767-1. BMC Med Genet. 2019. PMID: 30808328 Free PMC article.
Exploring Shared Susceptibility between Two Neural Crest Cells Originating Conditions: Neuroblastoma and Congenital Heart Disease.
Testori A, Lasorsa VA, Cimmino F, Cantalupo S, Cardinale A, Avitabile M, Limongelli G, Russo MG, Diskin S, Maris J, Devoto M, Keavney B, Cordell HJ, Iolascon A, Capasso M. Testori A, et al. Among authors: lasorsa va. Genes (Basel). 2019 Aug 30;10(9):663. doi: 10.3390/genes10090663. Genes (Basel). 2019. PMID: 31480262 Free PMC article.
Genomic coamplification of CDK4/MDM2/FRS2 is associated with very poor prognosis and atypical clinical features in neuroblastoma patients.
Amoroso L, Ognibene M, Morini M, Conte M, Di Cataldo A, Tondo A, D'Angelo P, Castellano A, Garaventa A, Lasorsa VA, Podestà M, Capasso M, Pezzolo A. Amoroso L, et al. Among authors: lasorsa va. Genes Chromosomes Cancer. 2020 May;59(5):277-285. doi: 10.1002/gcc.22827. Epub 2019 Dec 3. Genes Chromosomes Cancer. 2020. PMID: 31756773
38 results