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Genetic Profile of Endotoxemia Reveals an Association With Thromboembolism and Stroke.
Leskelä J, Toppila I, Härma MA, Palviainen T, Salminen A, Sandholm N, Pietiäinen M, Kopra E, Pais de Barros JP; FinnGen; Lassenius MI, Kumar A, Harjutsalo V, Roslund K, Forsblom C, Loukola A, Havulinna AS, Lagrost L, Salomaa V, Groop PH, Perola M, Kaprio J, Lehto M, Pussinen PJ. Leskelä J, et al. Among authors: lassenius mi. J Am Heart Assoc. 2021 Nov 2;10(21):e022482. doi: 10.1161/JAHA.121.022482. Epub 2021 Oct 20. J Am Heart Assoc. 2021. PMID: 34668383 Free PMC article.
Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.
Lassenius MI, Mäkinen VP, Fogarty CL, Peräneva L, Jauhiainen M, Pussinen PJ, Taskinen MR, Kirveskari J, Vaarala O, Nieminen JK, Hörkkö S, Kangas AJ, Soininen P, Ala-Korpela M, Gordin D, Ahola AJ, Forsblom C, Groop PH, Lehto M. Lassenius MI, et al. Nutr Metab (Lond). 2014 Jun 13;11:28. doi: 10.1186/1743-7075-11-28. eCollection 2014. Nutr Metab (Lond). 2014. PMID: 24959195 Free PMC article.
High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.
Fogarty CL, Nieminen JK, Peräneva L, Lassenius MI, Ahola AJ, Taskinen MR, Jauhiainen M, Kirveskari J, Pussinen P, Hörkkö S, Mäkinen VP, Gordin D, Forsblom C, Groop PH, Vaarala O, Lehto M. Fogarty CL, et al. Among authors: lassenius mi. Acta Diabetol. 2015 Apr;52(2):315-22. doi: 10.1007/s00592-014-0641-8. Epub 2014 Sep 3. Acta Diabetol. 2015. PMID: 25182144
Podocyte apoptosis is prevented by blocking the Toll-like receptor pathway.
Saurus P, Kuusela S, Lehtonen E, Hyvönen ME, Ristola M, Fogarty CL, Tienari J, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Holthöfer H, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Cell Death Dis. 2015 May 7;6(5):e1752. doi: 10.1038/cddis.2015.125. Cell Death Dis. 2015. PMID: 25950482 Free PMC article.
Cyclin-dependent kinase 2 protects podocytes from apoptosis.
Saurus P, Kuusela S, Dumont V, Lehtonen E, Fogarty CL, Lassenius MI, Forsblom C, Lehto M, Saleem MA, Groop PH, Lehtonen S. Saurus P, et al. Among authors: lassenius mi. Sci Rep. 2016 Feb 15;6:21664. doi: 10.1038/srep21664. Sci Rep. 2016. PMID: 26876672 Free PMC article.
Intestinal alkaline phosphatase at the crossroad of intestinal health and disease - a putative role in type 1 diabetes.
Lassenius MI, Fogarty CL, Blaut M, Haimila K, Riittinen L, Paju A, Kirveskari J, Järvelä J, Ahola AJ, Gordin D, Härma MA, Kumar A, Hamarneh SR, Hodin RA, Sorsa T, Tervahartiala T, Hörkkö S, Pussinen PJ, Forsblom C, Jauhiainen M, Taskinen MR, Groop PH, Lehto M; FinnDiane Study Group. Lassenius MI, et al. J Intern Med. 2017 Jun;281(6):586-600. doi: 10.1111/joim.12607. Epub 2017 Apr 10. J Intern Med. 2017. PMID: 28393441 Free article.
34 results