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Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures.
Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD, Grundberg E, Nethander M, Ohlsson C, Davey Smith G, Tobias JH. Zheng J, et al. Among authors: lerner uh. J Bone Miner Res. 2019 Oct;34(10):1824-1836. doi: 10.1002/jbmr.3803. Epub 2019 Aug 2. J Bone Miner Res. 2019. PMID: 31170332 Free PMC article.
The gut microbiota regulates bone mass in mice.
Sjögren K, Engdahl C, Henning P, Lerner UH, Tremaroli V, Lagerquist MK, Bäckhed F, Ohlsson C. Sjögren K, et al. Among authors: lerner uh. J Bone Miner Res. 2012 Jun;27(6):1357-67. doi: 10.1002/jbmr.1588. J Bone Miner Res. 2012. PMID: 22407806 Free PMC article.
WNT16 overexpression partly protects against glucocorticoid-induced bone loss.
Ohlsson C, Nilsson KH, Henning P, Wu J, Gustafsson KL, Poutanen M, Lerner UH, Movérare-Skrtic S. Ohlsson C, et al. Among authors: lerner uh. Am J Physiol Endocrinol Metab. 2018 Jun 1;314(6):E597-E604. doi: 10.1152/ajpendo.00292.2017. Epub 2018 Feb 6. Am J Physiol Endocrinol Metab. 2018. PMID: 29406783 Free article.
High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden Study.
Kristjansdottir HL, Lewerin C, Lerner UH, Waern E, Johansson H, Sundh D, Karlsson M, Cummings SR, Zetterberg H, Lorentzon M, Ohlsson C, Mellström D. Kristjansdottir HL, et al. Among authors: lerner uh. J Bone Miner Res. 2018 Sep;33(9):1560-1567. doi: 10.1002/jbmr.3443. Epub 2018 May 11. J Bone Miner Res. 2018. PMID: 29750841 Free article.
Osteoblast-derived NOTUM reduces cortical bone mass in mice and the NOTUM locus is associated with bone mineral density in humans.
Movérare-Skrtic S, Nilsson KH, Henning P, Funck-Brentano T, Nethander M, Rivadeneira F, Coletto Nunes G, Koskela A, Tuukkanen J, Tuckermann J, Perret C, Souza PPC, Lerner UH, Ohlsson C. Movérare-Skrtic S, et al. Among authors: lerner uh. FASEB J. 2019 Oct;33(10):11163-11179. doi: 10.1096/fj.201900707R. Epub 2019 Jul 15. FASEB J. 2019. PMID: 31307226 Free PMC article.
Osteocyte- and late osteoblast-derived NOTUM reduces cortical bone mass in mice.
Nilsson KH, Henning P, El Shahawy M, Wu J, Koskela A, Tuukkanen J, Perret C, Lerner UH, Ohlsson C, Movérare-Skrtic S. Nilsson KH, et al. Among authors: lerner uh. Am J Physiol Endocrinol Metab. 2021 May 1;320(5):E967-E975. doi: 10.1152/ajpendo.00565.2020. Epub 2021 Mar 22. Am J Physiol Endocrinol Metab. 2021. PMID: 33749332 Free article.
RSPO3 is important for trabecular bone and fracture risk in mice and humans.
Nilsson KH, Henning P, El Shahawy M, Nethander M, Andersen TL, Ejersted C, Wu J, Gustafsson KL, Koskela A, Tuukkanen J, Souza PPC, Tuckermann J, Lorentzon M, Ruud LE, Lehtimäki T, Tobias JH, Zhou S, Lerner UH, Richards JB, Movérare-Skrtic S, Ohlsson C. Nilsson KH, et al. Among authors: lerner uh. Nat Commun. 2021 Aug 13;12(1):4923. doi: 10.1038/s41467-021-25124-2. Nat Commun. 2021. PMID: 34389713 Free PMC article.
The WNT system: background and its role in bone.
Lerner UH, Ohlsson C. Lerner UH, et al. J Intern Med. 2015 Jun;277(6):630-49. doi: 10.1111/joim.12368. J Intern Med. 2015. PMID: 25845559 Free article. Review.
248 results