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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Freed-Pastor WA, Mizuno H, Zhao X, Langerød A, Moon SH, Rodriguez-Barrueco R, Barsotti A, Chicas A, Li W, Polotskaia A, Bissell MJ, Osborne TF, Tian B, Lowe SW, Silva JM, Børresen-Dale AL, Levine AJ, Bargonetti J, Prives C. Freed-Pastor WA, et al. Among authors: levine aj. Cell. 2012 Jan 20;148(1-2):244-58. doi: 10.1016/j.cell.2011.12.017. Cell. 2012. PMID: 22265415 Free PMC article.
Why are there hotspot mutations in the TP53 gene in human cancers?
Baugh EH, Ke H, Levine AJ, Bonneau RA, Chan CS. Baugh EH, et al. Among authors: levine aj. Cell Death Differ. 2018 Jan;25(1):154-160. doi: 10.1038/cdd.2017.180. Epub 2017 Nov 3. Cell Death Differ. 2018. PMID: 29099487 Free PMC article. Review.
The p53 functional circuit.
Jin S, Levine AJ. Jin S, et al. Among authors: levine aj. J Cell Sci. 2001 Dec;114(Pt 23):4139-40. doi: 10.1242/jcs.114.23.4139. J Cell Sci. 2001. PMID: 11739646 No abstract available.
Mutant p53 proteins bind DNA abnormally in vitro.
Kern SE, Kinzler KW, Baker SJ, Nigro JM, Rotter V, Levine AJ, Friedman P, Prives C, Vogelstein B. Kern SE, et al. Among authors: levine aj. Oncogene. 1991 Jan;6(1):131-6. Oncogene. 1991. PMID: 1846954
742 results