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A genome-wide assessment of variability in human serum metabolism.
Hong MG, Karlsson R, Magnusson PK, Lewis MR, Isaacs W, Zheng LS, Xu J, Grönberg H, Ingelsson E, Pawitan Y, Broeckling C, Prenni JE, Wiklund F, Prince JA. Hong MG, et al. Among authors: lewis mr. Hum Mutat. 2013 Mar;34(3):515-24. doi: 10.1002/humu.22267. Hum Mutat. 2013. PMID: 23281178
Metabolome-wide association study on ABCA7 indicates a role of ceramide metabolism in Alzheimer's disease.
Dehghan A, Pinto RC, Karaman I, Huang J, Durainayagam BR, Ghanbari M, Nazeer A, Zhong Q, Liggi S, Whiley L, Mustafa R, Kivipelto M, Solomon A, Ngandu T, Kanekiyo T, Aikawa T, Radulescu CI, Barnes SJ, Graça G, Chekmeneva E, Camuzeaux S, Lewis MR, Kaluarachchi MR, Ikram MA, Holmes E, Tzoulaki I, Matthews PM, Griffin JL, Elliott P. Dehghan A, et al. Among authors: lewis mr. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206083119. doi: 10.1073/pnas.2206083119. Epub 2022 Oct 21. Proc Natl Acad Sci U S A. 2022. PMID: 36269859 Free PMC article.
Urinary metabolic phenotyping for Alzheimer's disease.
Kurbatova N, Garg M, Whiley L, Chekmeneva E, Jiménez B, Gómez-Romero M, Pearce J, Kimhofer T, D'Hondt E, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Aarsland D, Nevado-Holgado A, Liu B, Snowden S, Proitsi P, Ashton NJ, Hye A, Legido-Quigley C, Lewis MR, Nicholson JK, Holmes E, Brazma A, Lovestone S. Kurbatova N, et al. Among authors: lewis mr. Sci Rep. 2020 Dec 10;10(1):21745. doi: 10.1038/s41598-020-78031-9. Sci Rep. 2020. PMID: 33303834 Free PMC article.
Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC).
Lippa KA, Aristizabal-Henao JJ, Beger RD, Bowden JA, Broeckling C, Beecher C, Clay Davis W, Dunn WB, Flores R, Goodacre R, Gouveia GJ, Harms AC, Hartung T, Jones CM, Lewis MR, Ntai I, Percy AJ, Raftery D, Schock TB, Sun J, Theodoridis G, Tayyari F, Torta F, Ulmer CZ, Wilson I, Ubhi BK. Lippa KA, et al. Among authors: lewis mr. Metabolomics. 2022 Apr 9;18(4):24. doi: 10.1007/s11306-021-01848-6. Metabolomics. 2022. PMID: 35397018 Free PMC article. Review.
Circulating Metabolome and White Matter Hyperintensities in Women and Men.
Sliz E, Shin J, Ahmad S, Williams DM, Frenzel S, Gauß F, Harris SE, Henning AK, Hernandez MV, Hu YH, Jiménez B, Sargurupremraj M, Sudre C, Wang R, Wittfeld K, Yang Q, Wardlaw JM, Völzke H, Vernooij MW, Schott JM, Richards M, Proitsi P, Nauck M, Lewis MR, Launer L, Hosten N, Grabe HJ, Ghanbari M, Deary IJ, Cox SR, Chaturvedi N, Barnes J, Rotter JI, Debette S, Ikram MA, Fornage M, Paus T, Seshadri S, Pausova Z; NeuroCHARGE Working Group. Sliz E, et al. Among authors: lewis mr. Circulation. 2022 Apr 5;145(14):1040-1052. doi: 10.1161/CIRCULATIONAHA.121.056892. Epub 2022 Jan 20. Circulation. 2022. PMID: 35050683 Free PMC article.
Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted 1H NMR Metabolic Profiling.
Castagné R, Boulangé CL, Karaman I, Campanella G, Santos Ferreira DL, Kaluarachchi MR, Lehne B, Moayyeri A, Lewis MR, Spagou K, Dona AC, Evangelos V, Tracy R, Greenland P, Lindon JC, Herrington D, Ebbels TMD, Elliott P, Tzoulaki I, Chadeau-Hyam M. Castagné R, et al. Among authors: lewis mr. J Proteome Res. 2017 Oct 6;16(10):3623-3633. doi: 10.1021/acs.jproteome.7b00344. Epub 2017 Sep 8. J Proteome Res. 2017. PMID: 28823158 Free PMC article.
Finding Correspondence between Metabolomic Features in Untargeted Liquid Chromatography-Mass Spectrometry Metabolomics Datasets.
Climaco Pinto R, Karaman I, Lewis MR, Hällqvist J, Kaluarachchi M, Graça G, Chekmeneva E, Durainayagam B, Ghanbari M, Ikram MA, Zetterberg H, Griffin J, Elliott P, Tzoulaki I, Dehghan A, Herrington D, Ebbels T. Climaco Pinto R, et al. Among authors: lewis mr. Anal Chem. 2022 Apr 12;94(14):5493-5503. doi: 10.1021/acs.analchem.1c03592. Epub 2022 Mar 31. Anal Chem. 2022. PMID: 35360896 Free PMC article.
Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping.
Lewis MR, Pearce JT, Spagou K, Green M, Dona AC, Yuen AH, David M, Berry DJ, Chappell K, Horneffer-van der Sluis V, Shaw R, Lovestone S, Elliott P, Shockcor J, Lindon JC, Cloarec O, Takats Z, Holmes E, Nicholson JK. Lewis MR, et al. Anal Chem. 2016 Sep 20;88(18):9004-13. doi: 10.1021/acs.analchem.6b01481. Epub 2016 Aug 26. Anal Chem. 2016. PMID: 27479709 Free article.
333 results