Lin S - Search Results

1

Design, synthesis, and biological evaluation of new-generation taxoids.

Ojima I, Chen J, Sun L, Borella CP, Wang T, Miller ML, Lin S, Geng X, Kuznetsova L, Qu C, Gallager D, Zhao X, Zanardi I, Xia S, Horwitz SB, Mallen-St Clair J, Guerriero JL, Bar-Sagi D, Veith JM, Pera P, Bernacki RJ. Ojima I, et al. Among authors: lin s. J Med Chem. 2008 Jun 12;51(11):3203-21. doi: 10.1021/jm800086e. Epub 2008 May 9. J Med Chem. 2008. PMID: 18465846 Free PMC article.

2

Design, synthesis and biological activity of novel C2-C3' N-Linked macrocyclic taxoids.

Ojima I, Geng X, Lin S, Pera P, Bernacki RJ. Ojima I, et al. Among authors: lin s. Bioorg Med Chem Lett. 2002 Feb 11;12(3):349-52. doi: 10.1016/s0960-894x(01)00747-8. Bioorg Med Chem Lett. 2002. PMID: 11814794

3

Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization.

Geng X, Miller ML, Lin S, Ojima I. Geng X, et al. Among authors: lin s. Org Lett. 2003 Oct 2;5(20):3733-6. doi: 10.1021/ol0354627. Org Lett. 2003. PMID: 14507217

4

Total synthesis of guanacastepene a: a route to enantiomeric control.

Mandal M, Yun H, Dudley GB, Lin S, Tan DS, Danishefsky SJ. Mandal M, et al. Among authors: lin s. J Org Chem. 2005 Dec 23;70(26):10619-37. doi: 10.1021/jo051470k. J Org Chem. 2005. PMID: 16355979

5

The total synthesis of proteasome inhibitors TMC-95A and TMC-95B: discovery of a new method to generate cis-propenyl amides.

Lin S, Danishefsky SJ. Lin S, et al. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):512-5. doi: 10.1002/1521-3773(20020201)41:3<512::aid-anie512>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491396 No abstract available.

6

Total synthesis of TMC-95A and -B via a new reaction leading to Z-enamides. Some preliminary findings as to SAR.

Lin S, Yang ZQ, Kwok BH, Koldobskiy M, Crews CM, Danishefsky SJ. Lin S, et al. J Am Chem Soc. 2004 May 26;126(20):6347-55. doi: 10.1021/ja049821k. J Am Chem Soc. 2004. PMID: 15149232 Free PMC article.

7

Simplified synthetic TMC-95A/B analogues retain the potency of proteasome inhibitory activity.

Yang ZQ, Kwok BH, Lin S, Koldobskiy MA, Crews CM, Danishefsky SJ. Yang ZQ, et al. Among authors: lin s. Chembiochem. 2003 Jun 6;4(6):508-13. doi: 10.1002/cbic.200300560. Chembiochem. 2003. PMID: 12794861 Free PMC article.

8

A stereoselective route to guanacastepene A through a surprising epoxidation.

Lin S, Dudley GB, Tan DS, Danishefsky SJ. Lin S, et al. Angew Chem Int Ed Engl. 2002 Jun 17;41(12):2188-91. Angew Chem Int Ed Engl. 2002. PMID: 19746640 No abstract available.

9

Synthesis of the Functionalized Macrocyclic Core of Proteasome Inhibitors TMC-95A and B This work was supported by grants from the National Institutes of Health (grant CA28824). We thank Dr. George Sukenick and Sylvi Rusli of the MSKCC NMR Core Facility for NMR and mass spectral analyses (NIH Grant CA08748).

Lin S, Danishefsky SJ. Lin S, et al. Angew Chem Int Ed Engl. 2001 May 18;40(10):1967-1970. Angew Chem Int Ed Engl. 2001. PMID: 11385688 No abstract available.

10

Sex Distributions in Non-ABCA4 Autosomal Macular Dystrophies.

Mishra AV, Vermeirsch S, Lin S, Martin-Gutierrez MP, Simcoe M, Pontikos N, Schiff E, de Guimarães TAC, Hysi PG, Michaelides M, Arno G, Webster AR, Mahroo OA. Mishra AV, et al. Among authors: lin s. Invest Ophthalmol Vis Sci. 2024 May 1;65(5):9. doi: 10.1167/iovs.65.5.9. Invest Ophthalmol Vis Sci. 2024. PMID: 38700873

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