Little JW - Search Results

1

The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.

Janes K, Little JW, Li C, Bryant L, Chen C, Chen Z, Kamocki K, Doyle T, Snider A, Esposito E, Cuzzocrea S, Bieberich E, Obeid L, Petrache I, Nicol G, Neumann WL, Salvemini D. Janes K, et al. Among authors: little jw. J Biol Chem. 2014 Jul 25;289(30):21082-97. doi: 10.1074/jbc.M114.569574. J Biol Chem. 2014. PMID: 24876379 Free PMC article.

2

Dysregulation of sphingolipid metabolism contributes to bortezomib-induced neuropathic pain.

Stockstill K, Doyle TM, Yan X, Chen Z, Janes K, Little JW, Braden K, Lauro F, Giancotti LA, Harada CM, Yadav R, Xiao WH, Lionberger JM, Neumann WL, Bennett GJ, Weng HR, Spiegel S, Salvemini D. Stockstill K, et al. Among authors: little jw. J Exp Med. 2018 May 7;215(5):1301-1313. doi: 10.1084/jem.20170584. Epub 2018 Apr 27. J Exp Med. 2018. PMID: 29703731 Free PMC article.

3

Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels through astrocyte-dependent mechanisms.

Wahlman C, Doyle TM, Little JW, Luongo L, Janes K, Chen Z, Esposito E, Tosh DK, Cuzzocrea S, Jacobson KA, Salvemini D. Wahlman C, et al. Among authors: little jw. Pain. 2018 Jun;159(6):1025-1034. doi: 10.1097/j.pain.0000000000001177. Pain. 2018. PMID: 29419652 Free PMC article.

4

Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.

Janes K, Wahlman C, Little JW, Doyle T, Tosh DK, Jacobson KA, Salvemini D. Janes K, et al. Among authors: little jw. Brain Behav Immun. 2015 Feb;44:91-9. doi: 10.1016/j.bbi.2014.08.010. Epub 2014 Sep 8. Brain Behav Immun. 2015. PMID: 25220279 Free PMC article.

5

Supraspinal peroxynitrite modulates pain signaling by suppressing the endogenous opioid pathway.

Little JW, Chen Z, Doyle T, Porreca F, Ghaffari M, Bryant L, Neumann WL, Salvemini D. Little JW, et al. J Neurosci. 2012 Aug 8;32(32):10797-808. doi: 10.1523/JNEUROSCI.6345-11.2012. J Neurosci. 2012. PMID: 22875915 Free PMC article.

6

Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance.

Little JW, Cuzzocrea S, Bryant L, Esposito E, Doyle T, Rausaria S, Neumann WL, Salvemini D. Little JW, et al. Pain. 2013 Jul;154(7):978-86. doi: 10.1016/j.pain.2013.02.018. Epub 2013 Feb 27. Pain. 2013. PMID: 23590939 Free PMC article.

7

Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states.

Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F, Jacobson KA, Salvemini D. Little JW, et al. Brain. 2015 Jan;138(Pt 1):28-35. doi: 10.1093/brain/awu330. Epub 2014 Nov 19. Brain. 2015. PMID: 25414036 Free PMC article.

8

Roles of reactive oxygen and nitrogen species in pain.

Salvemini D, Little JW, Doyle T, Neumann WL. Salvemini D, et al. Among authors: little jw. Free Radic Biol Med. 2011 Sep 1;51(5):951-66. doi: 10.1016/j.freeradbiomed.2011.01.026. Epub 2011 Jan 28. Free Radic Biol Med. 2011. PMID: 21277369 Free PMC article. Review.

9

Reactive nitroxidative species and nociceptive processing: determining the roles for nitric oxide, superoxide, and peroxynitrite in pain.

Little JW, Doyle T, Salvemini D. Little JW, et al. Amino Acids. 2012 Jan;42(1):75-94. doi: 10.1007/s00726-010-0633-0. Epub 2010 Jun 16. Amino Acids. 2012. PMID: 20552384 Review.

10

Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain.

Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Koninck Y, Tosh DK, Jacobson KA, Salvemini D. Ford A, et al. Among authors: little jw. J Neurosci. 2015 Apr 15;35(15):6057-67. doi: 10.1523/JNEUROSCI.4495-14.2015. J Neurosci. 2015. PMID: 25878279 Free PMC article.

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