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Use of serum C reactive protein and procalcitonin concentrations in addition to symptoms and signs to predict pneumonia in patients presenting to primary care with acute cough: diagnostic study.
van Vugt SF, Broekhuizen BD, Lammens C, Zuithoff NP, de Jong PA, Coenen S, Ieven M, Butler CC, Goossens H, Little P, Verheij TJ; GRACE consortium. van Vugt SF, et al. Among authors: little p. BMJ. 2013 Apr 30;346:f2450. doi: 10.1136/bmj.f2450. BMJ. 2013. PMID: 23633005 Free PMC article. Clinical Trial.
Predictors of poor outcome and benefits from antibiotics in children with acute otitis media: pragmatic randomised trial.
Little P, Gould C, Moore M, Warner G, Dunleavey J, Williamson I. Little P, et al. BMJ. 2002 Jul 6;325(7354):22; discussion 22. doi: 10.1136/bmj.325.7354.22. BMJ. 2002. PMID: 12098725 Free PMC article. Clinical Trial.
Among the children with high temperature or vomiting, distress by day three was less likely with immediate antibiotics (32% for immediate v 53% for delayed, chi2=4.0; P=0.045, number needed to treat 5) as was night disturbance (26% v 59%, chi2=9.3; P=0.002; number n …
Among the children with high temperature or vomiting, distress by day three was less likely with immediate antibiotics (32% for immediate v …
Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial.
Little P, Rumsby K, Kelly J, Watson L, Moore M, Warner G, Fahey T, Williamson I. Little P, et al. JAMA. 2005 Jun 22;293(24):3029-35. doi: 10.1001/jama.293.24.3029. JAMA. 2005. PMID: 15972565 Clinical Trial.
Compared with the immediate antibiotic group, slightly fewer patients in the delayed and control groups used antibiotics (96%, 20%, and 16%, respectively; P<.001), fewer patients were "very satisfied" (86%, 77%, and 72%, respectively; P = .005), and fewer patient …
Compared with the immediate antibiotic group, slightly fewer patients in the delayed and control groups used antibiotics (96%, 20%, and 16%, …
1,261 results