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Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong W, Pasunooti KK, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman ET, Dick T, Liu CF, Lescar J, Dedon PC. Zhong W, et al. Among authors: liu cf. J Med Chem. 2019 Sep 12;62(17):7788-7805. doi: 10.1021/acs.jmedchem.9b00582. Epub 2019 Aug 29. J Med Chem. 2019. PMID: 31442049 Free PMC article.
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens.
Yuan Y, Zallot R, Grove TL, Payan DJ, Martin-Verstraete I, Šepić S, Balamkundu S, Neelakandan R, Gadi VK, Liu CF, Swairjo MA, Dedon PC, Almo SC, Gerlt JA, de Crécy-Lagard V. Yuan Y, et al. Among authors: liu cf. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19126-19135. doi: 10.1073/pnas.1909604116. Epub 2019 Sep 3. Proc Natl Acad Sci U S A. 2019. PMID: 31481610 Free PMC article.
Four additional natural 7-deazaguanine derivatives in phages and how to make them.
Cui L, Balamkundu S, Liu CF, Ye H, Hourihan J, Rausch A, Hauß C, Nilsson E, Hoetzinger M, Holmfeldt K, Zhang W, Martinez-Alvarez L, Peng X, Tremblay D, Moinau S, Solonenko N, Sullivan MB, Lee YJ, Mulholland A, Weigele PR, de Crécy-Lagard V, Dedon PC, Hutinet G. Cui L, et al. Among authors: liu cf. Nucleic Acids Res. 2023 Sep 22;51(17):9214-9226. doi: 10.1093/nar/gkad657. Nucleic Acids Res. 2023. PMID: 37572349 Free PMC article.
A direct method for site-specific protein acetylation.
Li F, Allahverdi A, Yang R, Lua GB, Zhang X, Cao Y, Korolev N, Nordenskiöld L, Liu CF. Li F, et al. Among authors: liu cf. Angew Chem Int Ed Engl. 2011 Oct 4;50(41):9611-4. doi: 10.1002/anie.201103754. Epub 2011 Sep 16. Angew Chem Int Ed Engl. 2011. PMID: 21922615 No abstract available.
1,311 results