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The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer.
Munkley J, Oltean S, Vodák D, Wilson BT, Livermore KE, Zhou Y, Star E, Floros VI, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim RI, Robson CN, Leung HY, Harries LW, Rajan P, Mills IG, Elliott DJ. Munkley J, et al. Among authors: livermore ke. Oncotarget. 2015 Oct 27;6(33):34358-74. doi: 10.18632/oncotarget.6024. Oncotarget. 2015. PMID: 26452038 Free PMC article.
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability.
Munkley J, Vodak D, Livermore KE, James K, Wilson BT, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Robson CN, Mills IG, Rajan P, Elliott DJ. Munkley J, et al. Among authors: livermore ke. EBioMedicine. 2016 Jun;8:103-116. doi: 10.1016/j.ebiom.2016.04.018. Epub 2016 Apr 20. EBioMedicine. 2016. PMID: 27428423 Free PMC article.
The cancer-associated cell migration protein TSPAN1 is under control of androgens and its upregulation increases prostate cancer cell migration.
Munkley J, McClurg UL, Livermore KE, Ehrmann I, Knight B, Mccullagh P, Mcgrath J, Crundwell M, Harries LW, Leung HY, Mills IG, Robson CN, Rajan P, Elliott DJ. Munkley J, et al. Among authors: livermore ke. Sci Rep. 2017 Jul 12;7(1):5249. doi: 10.1038/s41598-017-05489-5. Sci Rep. 2017. PMID: 28701765 Free PMC article.
Androgen-dependent alternative mRNA isoform expression in prostate cancer cells.
Munkley J, Maia TM, Ibarluzea N, Livermore KE, Vodak D, Ehrmann I, James K, Rajan P, Barbosa-Morais NL, Elliott DJ. Munkley J, et al. Among authors: livermore ke. F1000Res. 2018 Aug 3;7:1189. doi: 10.12688/f1000research.15604.1. eCollection 2018. F1000Res. 2018. PMID: 30271587 Free PMC article.
ST6GAL1: A key player in cancer.
Garnham R, Scott E, Livermore KE, Munkley J. Garnham R, et al. Among authors: livermore ke. Oncol Lett. 2019 Aug;18(2):983-989. doi: 10.3892/ol.2019.10458. Epub 2019 Jun 7. Oncol Lett. 2019. PMID: 31423157 Free PMC article. Review.
Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer.
Munkley J, Li L, Krishnan SRG, Hysenaj G, Scott E, Dalgliesh C, Oo HZ, Maia TM, Cheung K, Ehrmann I, Livermore KE, Zielinska H, Thompson O, Knight B, McCullagh P, McGrath J, Crundwell M, Harries LW, Daugaard M, Cockell S, Barbosa-Morais NL, Oltean S, Elliott DJ. Munkley J, et al. Among authors: livermore ke. Elife. 2019 Sep 3;8:e47678. doi: 10.7554/eLife.47678. Elife. 2019. PMID: 31478829 Free PMC article.
ST6GAL1-mediated aberrant sialylation promotes prostate cancer progression.
Scott E, Archer Goode E, Garnham R, Hodgson K, Orozco-Moreno M, Turner H, Livermore K, Putri Nangkana K, Frame FM, Bermudez A, Jose Garcia Marques F, McClurg UL, Wilson L, Thomas H, Buskin A, Hepburn A, Duxfield A, Bastian K, Pye H, Arredondo HM, Hysenaj G, Heavey S, Stopka-Farooqui U, Haider A, Freeman A, Singh S, Johnston EW, Punwani S, Knight B, McCullagh P, McGrath J, Crundwell M, Harries L, Heer R, Maitland NJ, Whitaker H, Pitteri S, Troyer DA, Wang N, Elliott DJ, Drake RR, Munkley J. Scott E, et al. J Pathol. 2023 Sep;261(1):71-84. doi: 10.1002/path.6152. Epub 2023 Aug 7. J Pathol. 2023. PMID: 37550801 Free article.
The role of GCNT1 mediated O-glycosylation in aggressive prostate cancer.
Hodgson K, Orozco-Moreno M, Scott E, Garnham R, Livermore K, Thomas H, Zhou Y, He J, Bermudez A, Garcia Marques FJ, Bastian K, Hysenaj G, Archer Goode E, Heer R, Pitteri S, Wang N, Elliott DJ, Munkley J. Hodgson K, et al. Sci Rep. 2023 Oct 9;13(1):17031. doi: 10.1038/s41598-023-43019-8. Sci Rep. 2023. PMID: 37813880 Free PMC article.