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HIV-1 envelope gp41 antibodies can originate from terminal ileum B cells that share cross-reactivity with commensal bacteria.
Trama AM, Moody MA, Alam SM, Jaeger FH, Lockwood B, Parks R, Lloyd KE, Stolarchuk C, Scearce R, Foulger A, Marshall DJ, Whitesides JF, Jeffries TL Jr, Wiehe K, Morris L, Lambson B, Soderberg K, Hwang KK, Tomaras GD, Vandergrift N, Jackson KJL, Roskin KM, Boyd SD, Kepler TB, Liao HX, Haynes BF. Trama AM, et al. Among authors: lockwood b. Cell Host Microbe. 2014 Aug 13;16(2):215-226. doi: 10.1016/j.chom.2014.07.003. Cell Host Microbe. 2014. PMID: 25121750 Free PMC article.
Induction of HIV-1 broad neutralizing antibodies in 2F5 knock-in mice: selection against membrane proximal external region-associated autoreactivity limits T-dependent responses.
Verkoczy L, Chen Y, Zhang J, Bouton-Verville H, Newman A, Lockwood B, Scearce RM, Montefiori DC, Dennison SM, Xia SM, Hwang KK, Liao HX, Alam SM, Haynes BF. Verkoczy L, et al. Among authors: lockwood b. J Immunol. 2013 Sep 1;191(5):2538-50. doi: 10.4049/jimmunol.1300971. Epub 2013 Aug 5. J Immunol. 2013. PMID: 23918977 Free PMC article.
Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice.
Wiehe K, Nicely NI, Lockwood B, Kuraoka M, Anasti K, Arora S, Bowman CM, Stolarchuk C, Parks R, Lloyd KE, Xia SM, Duffy R, Shen X, Kyratsous CA, Macdonald LE, Murphy AJ, Scearce RM, Moody MA, Alam SM, Verkoczy L, Tomaras GD, Kelsoe G, Haynes BF. Wiehe K, et al. Among authors: lockwood b. J Immunol. 2017 Feb 1;198(3):1047-1055. doi: 10.4049/jimmunol.1601640. Epub 2016 Dec 23. J Immunol. 2017. PMID: 28011932 Free PMC article.
Leaning on Hope.
Lockwood BJ. Lockwood BJ. JAMA. 2022 Jun 7;327(21):2083-2084. doi: 10.1001/jama.2022.8428. JAMA. 2022. PMID: 35670786 No abstract available.
105 results