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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.
Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X; 23andMe Research Team; HUNT All-In Psychiatry; Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková A, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold B… See abstract for full author list ➔ Liu M, et al. Among authors: loukola a. Nat Genet. 2019 Feb;51(2):237-244. doi: 10.1038/s41588-018-0307-5. Epub 2019 Jan 14. Nat Genet. 2019. PMID: 30643251 Free PMC article.
Genetic linkage to chromosome 22q12 for a heavy-smoking quantitative trait in two independent samples.
Saccone SF, Pergadia ML, Loukola A, Broms U, Montgomery GW, Wang JC, Agrawal A, Dick DM, Heath AC, Todorov AA, Maunu H, Heikkila K, Morley KI, Rice JP, Todd RD, Kaprio J, Peltonen L, Martin NG, Goate AM, Madden PA. Saccone SF, et al. Among authors: loukola a. Am J Hum Genet. 2007 May;80(5):856-66. doi: 10.1086/513703. Epub 2007 Mar 26. Am J Hum Genet. 2007. PMID: 17436240 Free PMC article.
Genetic linkage findings for DSM-IV nicotine withdrawal in two populations.
Pergadia ML, Agrawal A, Loukola A, Montgomery GW, Broms U, Saccone SF, Wang JC, Todorov AA, Heikkilä K, Statham DJ, Henders AK, Campbell MJ, Rice JP, Todd RD, Heath AC, Goate AM, Peltonen L, Kaprio J, Martin NG, Madden PA. Pergadia ML, et al. Among authors: loukola a. Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):950-9. doi: 10.1002/ajmg.b.30924. Am J Med Genet B Neuropsychiatr Genet. 2009. PMID: 19180564 Free PMC article.
Associations of nicotine intake measures with CHRN genes in Finnish smokers.
Keskitalo-Vuokko K, Pitkäniemi J, Broms U, Heliövaara M, Aromaa A, Perola M, Ripatti S, Salminen O, Salomaa V, Loukola A, Kaprio J. Keskitalo-Vuokko K, et al. Among authors: loukola a. Nicotine Tob Res. 2011 Aug;13(8):686-90. doi: 10.1093/ntr/ntr059. Epub 2011 Apr 16. Nicotine Tob Res. 2011. PMID: 21498873 Free PMC article.
A 3p26-3p25 genetic linkage finding for DSM-IV major depression in heavy smoking families.
Pergadia ML, Glowinski AL, Wray NR, Agrawal A, Saccone SF, Loukola A, Broms U, Korhonen T, Penninx BW, Grant JD, Nelson EC, Henders AK, Schrage AJ, Chou YL, Keskitalo-Vuokko K, Zhu Q, Gordon SD, Vink JM, de Geus EJ, Macgregor S, Liu JZ, Willemsen G, Medland SE, Boomsma DI, Montgomery GW, Rice JP, Goate AM, Heath AC, Kaprio J, Martin NG, Madden PA. Pergadia ML, et al. Among authors: loukola a. Am J Psychiatry. 2011 Aug;168(8):848-52. doi: 10.1176/appi.ajp.2011.10091319. Epub 2011 May 15. Am J Psychiatry. 2011. PMID: 21572167 Free PMC article.
Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.
Broms U, Wedenoja J, Largeau MR, Korhonen T, Pitkäniemi J, Keskitalo-Vuokko K, Häppölä A, Heikkilä KH, Heikkilä K, Ripatti S, Sarin AP, Salminen O, Paunio T, Pergadia ML, Madden PA, Kaprio J, Loukola A. Broms U, et al. Among authors: loukola a. Nicotine Tob Res. 2012 Jun;14(6):720-33. doi: 10.1093/ntr/ntr283. Epub 2012 Jan 12. Nicotine Tob Res. 2012. PMID: 22241830 Free PMC article.
131 results